Hederagenin suppresses ovarian cancer via targeting mitochondrial fission through dynamin-related protein 1.
Hederagenin, a compound from Hedera helix, has anti-cancer, anti-inflammatory, anti-depressant, and anti-fibrosis properties. This study shows that hederagenin suppresses ovarian cancer cell growth, induces apoptosis, alters mitochondrial morphology, and modulates the protein Drp1 to inhibit cancer progression.
- Su F et al (2023).
- Eur J Pharmacol.
- PubMed:
- 37951490