Anti-α-glucosidase, Anti-proliferative and Anti-enterovirus 71 Activity of Secondary Metabolites Identified from Grifola Frondosa.

Researchers found that compounds derived from Grifola frondosa, an edible and medicinal resource, show inhibitory activity against α-glucosidase, tumor cells, and enterovirus 71 (EV71). This discovery could lead to potential treatments for diabetes, cancer, and EV71 infections.

He J et al (2023).

Plant Foods Hum Nutr.

DOI:

10.1007/s11130-023-01106-1

PubMed:

37812276

Identification of novel inhibitors from Urtica spp against TNBC targeting JAK2 receptor for breast cancer therapy.

Researchers discovered extracts from Urtica dioica and U. parviflora plants containing 12 compounds with better binding energy than Paclitaxel. These extracts showed promising anticancer activity against TNBC cells while being less toxic to healthy cells, hinting at herbal-based drug development for breast cancer.

Upreti S et al (2023).

Med Oncol.

DOI:

10.1007/s12032-023-02193-5

PubMed:

37806999

Evaluation of anticancer effect of colchicum autumnale L. Corm on breast cancer cell.

Study evaluated anticancer effect of colchicum autumnale L. Corm on breast cancer cells. Medicinal plants could potentially prevent and inhibit breast cancer. Important for lab decisions on cancer research.

Falahianshafiei S et al (2023).

BMC Complement Med Ther.

DOI:

10.1186/s12906-023-04189-0

PubMed:

37805533

HPLC-ESI/MS-MS characterization of compounds in Dolomiaea costus extract and evaluation of cytotoxic and antiviral properties: molecular mechanisms underlying apoptosis-inducing effect on breast cancer.

Researchers identified the components in Dolomiaea costus extract and tested its effects on breast cancer cells and a virus. It has potential for cancer treatment and antiviral therapy.

El-Nashar HAS et al (2023).

BMC Complement Med Ther.

DOI:

10.1186/s12906-023-04164-9

PubMed:

37803435

[Prediction and analysis of Q-markers of Elephantopus scaber based on its UPLC fingerprint, content determination of components, and in vitro a nti-tumor activity].

This study analyzed Elephantopus scaber using UPLC to determine its quality markers and identified 13 major components. The main components showed strong anti-cancer activity against lung cancer cells, making them potential quality markers for E. scaber.

Jia CC et al (2023).

Zhongguo Zhong Yao Za Zhi.

DOI:

10.19540/j.cnki.cjcmm.20230526.201

PubMed:

37802868

Down-regulation of human papillomavirus E6 oncogene and antiproliferative effect of Schisandra chinensis and Pueraria lobata natural extracts on Hela cell line.

Cardona-Mendoza A et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117225

PubMed:

37797877

Antiproliferative Activity of Lignans from Olea ferruginea: In Vitro Evidence Supported by Docking Studies.

This study explored the anticancer effects of bioactive compounds from the leaves of a plant. Previous studies found these compounds had antibacterial, antileishmanial, and antioxidant properties, but now we investigate their potential in slowing down cancer cell growth.

Rauf A et al (2023).

Front Biosci (Landmark Ed).

DOI:

10.31083/j.fbl2809216

PubMed:

37796717

Network pharmacology-based anti-colorectal cancer activity of piperlonguminine in the ethanolic root extract of Piper longum L.

Researchers studied the ethanolic root extract of Piper longum and identified piperlonguminine as a potential medicine for colorectal cancer. Hub genes SRC, MTOR, EZH2, and MAPK3 were found to be involved in cancer-related pathways that could be targeted for treatment. Piperlonguminine shows promise as a future CRC medicine.

Singh I, Das R and Kumar A (2023).

Med Oncol.

DOI:

10.1007/s12032-023-02185-5

PubMed:

37796360