GeoBotanical: Cardiology Studies

49.

Investigation of the efficacy of Dengzhan Shengmai capsule against heart failure with preserved ejection fraction.

Chinese medicine DZSMC may treat HFpEF effectively. Research on its mechanism is growing. Potential safe and effective treatment worth exploring further for high mortality condition.

Cardiology Erigeron breviscapus Ophiopogon japonicus Schisandra chinensis

Kang Z et al (2024).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2024.118419
PubMed:: 38838924

50.

Phelligridimer A enhances the expression of mitofusin 2 and protects against cerebral ischemia/reperfusion injury.

PA, an active compound from Phellinus igniarius, protects against cerebral ischemic injury by restoring mitochondrial function and reducing ER stress in both in vitro and in vivo models. This suggests PA could be a novel therapeutic agent for ischemic stroke.

Cardiology Phellinus igniarius

Li X et al (2024).; Chem Biol Interact.
DOI:: 10.1016/j.cbi.2024.111090
PubMed:: 38825057

51.

Notoginseng leaf triterpenes promotes angiogenesis by activating the Nrf2 pathway and AMPK/SIRT1-mediated PGC-1/ERα axis in ischemic stroke.

Notoginseng leaf triterpenes enhance angiogenesis after stroke by activating Nrf2 and AMPK/SIRT1 pathways, promoting neuroprotection and neuronal regeneration. Potential future stroke treatment.

Cardiology Neuroscience Panax notoginseng

Wang L et al (2024).; Fitoterapia.
DOI:: 10.1016/j.fitote.2024.106045
PubMed:: 38823597

52.

Acorus tatarinowii oils exert protective effects on microglia-mediated inflammatory injury via restoring gut microbiota composition in experimental stroke rats.

Researchers studied the effects of Acorus tatarinowii oils on microglial inflammation after ischemic stroke. Results showed AT oils reduced cerebral damage, inflammation, and improved gut microbiota balance. Gut microbiota played a crucial role in the protective effects of AT oils.

Cardiology Gastroenterology Immunology Neuroscience Acorus tatarinowii

Huang Y et al (2024).; Brain Res Bull.
DOI:: 10.1016/j.brainresbull.2024.110990
PubMed:: 38821245

53.

Assessing cardiovascular benefits of beetroot juice and exercise in women planning to conceive: reply to correspondence.

Cardiology Beta vulgaris

Osman MMA, Mullins E and Lees C (2024).; J Hypertens.
DOI:: 10.1097/HJH.0000000000003734
PubMed:: 38818843

54.

Assessing cardiovascular benefits of beetroot juice and exercise in women planning to conceive.

Cardiology Beta vulgaris

Islam H et al (2024).; J Hypertens.
DOI:: 10.1097/HJH.0000000000003660
PubMed:: 38818840

55.

Danshen injection mitigated the cerebral ischemia/reperfusion injury by suppressing neuroinflammation via the HIF-1α/CXCR4/NF-κB signaling pathway.

Danshen injection (DI) treats cardiovascular and brain diseases, improves neurological scores and reduces inflammation and oxidative stress. DI targets HIF-1α to suppress neuroinflammation and reduce ischemia/reperfusion injury.

Cardiology Immunology Neuroscience Salvia Salvia miltiorrhiza

Chen G et al (2024).; Neuroreport.
DOI:: 10.1097/WNR.0000000000002043
PubMed:: 38813902

56.

Breviscapine ameliorates autophagy by activating the JAK2/STAT5/BCL2 pathway in a transient cerebral ischemia rat model.

Breviscapine (Bre) from Erigeron breviscapus reduces ischemic brain damage by decreasing excessive autophagy. Activating JAK2/STAT5/BCL2 pathway improves neural recovery. Potential therapy for cerebral ischemia.

Cardiology Immunology Erigeron breviscapus

Cun Y et al (2024).; J Neuropathol Exp Neurol.
DOI:: 10.1093/jnen/nlae045
PubMed:: 38804899