Tossers studied binding between HCQ/SM and HSA, inducing conformational changes, with potential therapeutic relevance for COVID-19 due to strong interaction with virus proteases. Valuable insights for pharmaceutical and biological properties.
Opium use impacts COVID-19 severity, with higher hypertension and urea levels, lower lymphocytes, and increased risk of hospitalization and mortality. You should care because opium use affects the outcome of COVID-19 patients.
Researchers found potential antiviral compounds from traditional Chinese medicine that showed inhibitory effects on SARS-CoV-2 proteases. Compound 1,5,7-guaiane-4,10-diol-6-one demonstrated the best inhibitory activity. These findings could lead to the development of new antiviral treatments for COVID-19.
Researchers studied the antiviral effects of the plant compound Mauritine on COVID-19 protease. Mauritine-A and Mauritine-C show promise with strong binding affinity and stability. This could lead to potential COVID-19 treatments.
Wild forest mushrooms such as Pleurotus ostreatus and Phallus luteus show promise as antiviral agents against coronaviruses, including SARS-CoV-2. Controlling CoV infections in animals is crucial for preventing human outbreaks. This research suggests a potential new avenue for coronavirus treatment using natural resources.
In Senegal, local medicinal plants from families Combretaceae, Fabaceae, Myrtaceae, and Rubiaceae are commonly used to treat respiratory infections. Understanding their effectiveness can inform treatment strategies in the region.
Summary: β-escin from Aesculus hippocastanum has anti-inflammatory effects and affects NF-κB signaling. It shows promising broad-spectrum antiviral activity against coronaviruses including SARS-CoV-2, with potential as a therapeutic option for respiratory virus outbreaks.
"Eucalyptus citriodora essential oil shows strong potential against SARS-CoV-2. Globulol is a key compound. In silico and in vitro studies support its effectiveness. Promising for future COVID-19 research."