Diabetes Studies

New anti-diabetic drug Morus alba L. (Sangzhi) alkaloids (SZ-A) improves diabetic nephropathy through ameliorating inflammation and fibrosis in diabetic rats.

The study investigated the effects of SZ-A, a newly approved antidiabetic drug, on diabetic nephropathy. It provides valuable insights for potential treatment options and improving the health outcomes of patients with this complication.

Li C et al (2023).
Front Med (Lausanne).
PubMed:
37359004

Urtica dioica (Gazaneh) distillate restores glucose metabolism in diabetic rats.

This study investigates the potential antidiabetic effects of on glucose metabolism in diabetic rats. These findings may contribute to improving diabetes treatment strategies.

Zamani-Garmsiri F et al (2023).
Int J Prev Med.
PubMed:
37351057

Network pharmacology and multitarget analysis of Nigella sativa in the management of diabetes and obesity: a computational study.

Scientists identified potential compounds from black cumin that can inhibit protein targets and pathways associated with diabetes and obesity. Kaempferol was found to be the best binder for AKT1.

Saleem M et al (2023).
J Biomol Struct Dyn.
PubMed:
37350443

The kidney antifibrotic effects of 5,7,3',4',5'-pentamethoxyflavone from Bauhinia championii in streptozotocin-induced diabetic rats: in vivo and in vitro experiments.

Researchers investigated the antidiabetic effects of a flavonoid called 5,7,3',4',5'-pentamethoxyflavone isolated from Benth. (Fabaceae) and confirmed its potential as a treatment for diabetes.

Li J et al (2023).
Pharm Biol.
PubMed:
37345554

Chemical constituents from Acorus calamus with potent anti-diabetic and hepatoprotective activities.

Scientists isolated and identified new compounds from Acorus calamus Linn. rhizomes. Compound 5 showed significant GK activating activity and compound 3 exhibited moderate hepatoprotective effects. Structural insights were investigated through molecular docking.

Hao Z et al (2023).
Fitoterapia.
PubMed:
37343685

Modulatory role of Coriandrum sativum (coriander) extract against diabetic complications on the gonads of female rats and their offspring.

Coriander extract improved diabetic gonadal dysfunctions in female rats and their offspring by mitigating histological, immunohistochemical, biochemical, and apoptotic alterations.

Attaallah A et al (2023).
Tissue Cell.
PubMed:
37331322

Glycemic Index and Glycemic Load of Two Dishes Cooked with Alache (Anoda cristata) and Chaya (Cnidoscolus aconitifolius) Plants from the Traditional Mexican Diet.

This study measured the glycemic index and glycemic load of white rice and tamal prepared with and without two species of quelites. Quelites could be a good alternative for healthy diets.

Morales-Guerrero JC et al (2023).
J Med Food.
PubMed:
37319313