Diabetes Studies

Isolation of phenolic compound from Lawsonia inermis and its prediction as anti-diabetic agent using molecular docking and molecular dynamic simulation.

Scientists isolated and characterized a phenolic compound from the henna plant that has the potential as an anti-diabetic agent. The compound showed a high affinity for specific enzymes and was well-predicted in terms of skin permeability and distribution. Potential for new diabetes medication.

DiabetesPhytochemistry Lawsonia inermis
Musfiroh I et al (2023).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2023.2262595
PubMed:
37776010

Counteractive role of Terminalia catappa leaf extract on hematological and coagulation disturbance in Type 2 diabetic rats.

This study investigates the effect of leaf extract on blood abnormalities and clotting problems in Type 2 diabetic rats, which could help improve treatment strategies for diabetes-related complications.

Diabetes Terminalia catappa
Iheagwam FN et al (2023).
Vet World.
DOI:
10.14202/vetworld.2023.1593-1599
PubMed:
37766705

Antioxidant Effect of the Ethyl Acetate Extract of Potentilla indica on Kidney Mitochondria of Streptozotocin-Induced Diabetic Rats.

Researchers investigated the antioxidant effect of the ethyl acetate extract of on diabetic rats. The extract reduced oxidative stress and improved kidney function, suggesting it may have renoprotective effects for diabetic patients.

DiabetesImmunology Potentilla indica
Landa-Moreno CI et al (2023).
Plants (Basel).
DOI:
10.3390/plants12183196
PubMed:
37765360

Antioxidant, Antiglaucoma, Anticholinergic, and Antidiabetic Effects of Kiwifruit (Actinidia deliciosa) Oil: Metabolite Profile Analysis Using LC-HR/MS, GC/MS and GC-FID.

Kiwifruit oil contains various phenolic compounds with antioxidant properties. It also exhibits inhibitory effects on enzymes linked to metabolic diseases like Alzheimer's and diabetes. The oil shows potential for pharmaceutical applications.

DiabetesImmunology Actinidia deliciosa
Ozden EM et al (2023).
Life (Basel).
DOI:
10.3390/life13091939
PubMed:
37763342

Comprehensive Overview of the Effects of Amaranthus and Abelmoschus esculentus on Markers of Oxidative Stress in Diabetes Mellitus.

Selected plants show potential in alleviating oxidative stress in diabetes, but more research is required to confirm their effectiveness in humans. Further clinical studies, particularly in Africa, are recommended to explore their benefits in diabetes management.

DiabetesImmunology Abelmoschus esculentusAmaranthus hybridusAmaranthus spinosus
Phoswa WN and Mokgalaboni K (2023).
Life (Basel).
DOI:
10.3390/life13091830
PubMed:
37763234

The Possibility of Using Fruit-Bearing Plants of Temperate Climate in the Treatment and Prevention of Diabetes.

This review suggests that alternative fruit species such as Cornelian cherry, mulberry, bird cherry, and sour cherry have potential health benefits, including antidiabetic effects attributed to polyphenols. These fruits could be used in the treatment of diabetes and related complications.

Diabetes Cornus masCydonia oblongaMespilus germanica
Łysiak GP and Szot I (2023).
Life (Basel).
DOI:
10.3390/life13091795
PubMed:
37763199

Actinidia deliciosa Extract as a Promising Supplemental Agent for Hepatic and Renal Complication-Associated Type 2 Diabetes (In Vivo and In Silico-Based Studies).

This study found that kiwi extract can improve liver and kidney damage in rats with Type 2 diabetes. It reduces inflammation, oxidative stress, and apoptosis, and activates the insulin signaling pathway. Certain components of kiwi extract have potential as natural products for treating diabetes.

Diabetes Actinidia deliciosa
El Azab EF et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms241813759
PubMed:
37762060

Analysis of the Chemical Composition and Evaluation of the Antioxidant, Antimicrobial, Anticoagulant, and Antidiabetic Properties of Pistacia lentiscus from Boulemane as a Natural Nutraceutical Preservative.

The study analyzed the chemical profile of L. leaves and its effects. The leaves contain germacrene D, spathulenol, bicyclogermacrene, and terpinen-4-ol. L. is rich in phenolic compounds, has antioxidant and antimicrobial properties, and has potential as an anticoagulant and antidiabetic agent.

AntimicrobialDiabetesImmunology Pistacia lentiscus
Drioiche A et al (2023).
Biomedicines.
DOI:
10.3390/biomedicines11092372
PubMed:
37760813
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