Andrographis paniculata fractions improved glucose uptake in adipocytes and contained potential antidiabetic chemicals. Andrographolide and 14-deoxyandrographolide showed promise for type 2 diabetes treatment.
The study showed that the ethanolic extract of L. plant can improve male sexual dysfunction caused by diabetes in rats. It increases testosterone, hormones, antioxidant levels, and reduces oxidative stress. Molecular docking study revealed potential compounds with high binding affinity to PDE5 enzyme, suggesting aphrodisiac effects.
This study investigated medicinal plants used by herbalists in Ghana for managing diabetes and hypertension. 39 species of plants were identified, 18 for hypertension, 12 for diabetes, and 9 for both. Some of these plants have potential therapeutic benefits, but clinical studies are needed for confirmation.
Immature persimmons contain Hederagenin, Ursolic acid, and Quercetin dehydrate, which inhibit α-amylase and α-glucosidase enzymes, reducing hyperglycemia. They have potential for treating diabetes mellitus.
TLAF, a compound from Arctii Fructus, showed low toxicity in rats at 1,800 mg/kg for 26 weeks. It has potential for clinical treatment of diabetes.
A cucurbitane-type triterpene exhibited anti-diabetic properties, showing favorable binding energy, stability, pharmacokinetic, and toxicity properties. It has potential as an anti-diabetic drug candidate, but further research is needed.
Tossers investigated LCR, a compound found in plants, for treating diabetic wounds. They found it promotes autophagy and activates SIRT signaling, reducing inflammation and oxidative stress, enhancing cell survival and angiogenesis. LCR shows potential as a therapeutic agent for diabetic wounds.