Diabetes Studies

Chronic supplementation of noni in diabetic type 1-STZ rats: effects on glycemic levels, kidney toxicity and exercise performance.

Chronic noni fruit juice supplementation improved exercise performance and blood glucose control in rats with diabetes, but also caused kidney damage. Care should be taken when considering noni for clinical use.

Diabetes Morinda citrifolia
de Oliveira Fernandes D et al (2023).
Diabetol Metab Syndr.
DOI:
10.1186/s13098-023-01171-1
PubMed:
37794521

Asiaticoside-nitric oxide promoting diabetic wound healing through the miRNA-21-5p/TGF-β1/SMAD7/TIMP3 signaling pathway.

Researchers investigated the pharmacological properties of asiaticoside, a bioactive component of Centella asiatica, and found it has various benefits including wound-healing, anti-inflammatory, antioxidant, and anti-tumor activities.

Diabetes Centella asiatica
Liu Y et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117266
PubMed:
37783408

An in-vitro evaluation of antifungal, anti-lungcancer (A549), and anti-hyperglycemic activities potential of Andrographis paniculata (Burm. f.) flower extract.

Andrographis paniculata flower extract shows promise as an antifungal agent, inhibiting lung cancer cell growth and exhibiting anti-diabetic properties. Its bioactive compounds make it suitable for biomedical applications.

AntimicrobialDiabetes Andrographis paniculata
Phuong TN et al (2023).
Environ Res.
DOI:
10.1016/j.envres.2023.117249
PubMed:
37783331

Correction to: Capsicum annuum L. cv. DANGJO ameliorated hyperglycemia in type 2 diabetes animal model induced by high-fat diet and streptozotocin.

This study corrects a previous article. It is important for you to care because accurate information is crucial for making informed decisions in your lab.

Diabetes Capsicum annuum
Kim JT et al (2022).
Food Sci Biotechnol.
DOI:
10.1007/s10068-022-01081-4
PubMed:
37781059

Effects of Tectona grandis L. Extract in Diabetic Rats on Nitric Oxide and Malondialdehyde Levels.

The study found that the ethanol extract of teak leaves reduced nitric oxide and malondialdehyde levels in diabetic rats by acting as an antioxidant. This suggests potential benefits of teak leaf extract in managing diabetes.

Diabetes Tectona grandis
Parawansah et al (2023).
Pak J Biol Sci.
DOI:
10.3923/pjbs.2023.177.184
PubMed:
37779332

Screening and identification of potential hypoglycemic and hypolipidemic compounds from aqueous extract of Scutellaria baicalensis Georgi root combing affinity ultrafiltration with multiple drug targets and in silico analysis.

Scientists studied Scutellaria baicalensis Georgi, a traditional Chinese medicine often used in East Asia. They explored its active compounds in aqueous extracts and their effects on lowering blood sugar and lipids. The results may uncover the mechanisms behind its therapeutic properties.

Diabetes Scutellaria baicalensis
Xu Y et al (2023).
Phytochem Anal.
DOI:
10.1002/pca.3285
PubMed:
37779216

Effect of Crocus sativus L. (saffron) and crocin in the treatment of patients with type-2 diabetes mellitus: A systematic review and meta-analysis.

Crocus sativus (saffron) has been used as herbal medicine for T2DM in Sri Lanka. Systematic reviews and meta-analysis support its effectiveness, validating traditional knowledge.

Diabetes Crocus sativus
Amatto PPG et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117255
PubMed:
37778521

Acemannan ameliorates STZ-activated diabetes by attenuating high glucose via inhibiting inflammatory cytokines and apoptosis pathway.

Acemannan, a polysaccharide in Aloe vera, shows potential as an anti-diabetic agent. It effectively improved various biochemical parameters and had strong binding affinity to inflammatory markers. It could be a valuable treatment option for diabetes.

DiabetesImmunology Aloe vera
Omer AB et al (2023).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.127127
PubMed:
37776926
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