Arctium lappa L. roots inhibit the intestinal inflammation of dietary obese rats through TLR4/NF-κB pathway.

Long-term consumption of L. root powder (ARP) leads to weight loss. ARP inhibits pro-inflammatory cytokines, down-regulates genes involved in TLR4 complexes, and reduces inflammation in the colons of obese rats. ARP has potential in improving intestinal health and treating obesity.

Zeng F et al (2023).

Heliyon.

DOI:

10.1016/j.heliyon.2023.e21562

PubMed:

38027866

Saposhnikovia divaricata root and its major components ameliorate inflammation and altered gut microbial diversity and compositions in DSS-induced colitis.

Erdenebileg S et al (2023).

Integr Med Res.

DOI:

10.1016/j.imr.2023.100998

PubMed:

38024289

Protective effect of Melissa officinalis against acetic acid-induced ulcerative colitis in rat models: an experimental study.

Shahriarirad R et al (2023).

Ann Gastroenterol.

DOI:

10.20524/aog.2023.0836

PubMed:

38023971

Persea americana extract protects intestinal tissue from Eimeria papillata-induced murine Infection.

Alajmi F et al (2023).

BMC Vet Res.

DOI:

10.1186/s12917-023-03810-1

PubMed:

38017513

Preliminary data on cytotoxicity and functional group assessment of a herb-mineral combination against colorectal carcinoma cell line.

Jayakumar R et al (2023).

J Complement Integr Med.

DOI:

10.1515/jcim-2023-0221

PubMed:

38016708

N6-methyladenosine modification of TSC1 mRNA contributes to macrophage polarization regulated by Coptisine in DSS-induced ulcerative colitis.

This study investigates how coptisine (COP), derived from Coptis chinensis, inhibits macrophage inflammation in ulcerative colitis (UC). COP's protective mechanism against UC in mice induced with dextran sulfate sodium (DSS) is explored.

Zhao M et al (2024).

Phytomedicine.

DOI:

10.1016/j.phymed.2023.155153

PubMed:

38014839

Curcumin suppresses the Wnt/β-catenin signaling pathway by inhibiting NKD2 methylation to ameliorate intestinal ischemia/reperfusion injury.

Curcumin (CCM) reduces inflammation, cell apoptosis, and oxidative stress caused by intestinal ischemia/reperfusion (I/R) injury. It mediates these effects by inhibiting the Wnt/β-catenin signaling pathway through NKD2 methylation. Promising treatment for I/R injury.

Zhu JX et al (2023).

Kaohsiung J Med Sci.

DOI:

10.1002/kjm2.12782

PubMed:

38010861

Chaenomeles sinensis polysaccharide and its carboxymethylated derivative alleviate dextran sulfate sodium-induced ulcerative colitis via suppression of inflammation and oxidative stress.

Li C et al (2023).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2023.115941

PubMed:

38006619