Immunology Studies

Hamamelis virginiana L. extract presents antimicrobial and antibiofilm effects, absence of cytotoxicity, anti-inflammatory action, and potential to fight infections through the nitric oxide production by macrophages.

H. virginiana L. extract showed antimicrobial and antibiofilm effects, no cytotoxicity, anti-inflammatory action, and potential to fight infections through nitric oxide production, making it a promising treatment option.

Amêndola I et al (2024).
An Acad Bras Cienc.
PubMed:
38359287

The anti-inflammatory activity of flavonoids and alkaloids from Sophora flavescens alleviates psoriasiform lesions: Prenylation and methoxylation beneficially enhance bioactivity and skin targeting.

Researchers examined the anti-inflammatory effects of Sophora flavescens, finding that flavonoids had stronger inhibition of cytokine production than alkaloids, with prenylated flavanones offering the highest suppression. Prenylation and methoxylation of flavanones improved skin absorption and decreased epidermal thickness in mice, indicating potential for designing new treatments for psoriasis.

Lin CF et al (2024).
Phytother Res.
PubMed:
38358770

Anti-inflammatory, antioxidant, and immunomodulatory effects of Berberis vulgaris and its constituent berberine, experimental and clinical, a review.

Review on Berberis vulgaris (barberry) and berberine highlights their potential as anti-inflammatory and antioxidant agents. They inhibit pro-inflammatory cytokines, increase anti-inflammatory cytokines, scavenge free radicals, and reduce oxidative stress. They show promise in various diseases, but further research is required for optimal use and safety.

Shakeri F et al (2024).
Phytother Res.
PubMed:
38358731

Cannabidiol activates MAPK pathway to induce apoptosis, paraptosis, and autophagy in colorectal cancer cells.

CBD, found in Cannabis sativa, induces cell death in colorectal cancer cells. It activates the MAPK pathway, leading to apoptosis, paraptosis, and autophagy. This suggests that CBD could be a potential treatment for colorectal cancer.

Kim NY et al (2024).
J Cell Biochem.
PubMed:
38358093

The Phenolic Content of Pistacia lentiscus Leaf Extract and Its Antioxidant and Antidiabetic Properties.

This study examined the polyphenolic profile of leaves and their potential antioxidant and antidiabetic activities. The extract showed high levels of phenolic and flavonoid compounds and demonstrated significant inhibition of pancreatic alpha-amylase activity. This suggests potential benefits for diabetes treatment.

Bouakline H et al (2024).
ScientificWorldJournal.
PubMed:
38356989

Ganoderma lucidum: Insight into antimicrobial and antioxidant properties with development of secondary metabolites.

Researchers are studying the bioactive compounds in a versatile mushroom for potential disease treatments, including their antimicrobial and antioxidant properties.

Ahmad MF et al (2024).
Heliyon.
PubMed:
38356540