Immunology Studies

Effects of the compound extracts of Caprifoliaceae and Scutellaria baicalensis Georgi on the intestinal microbiota and antioxidant function.

This study investigated the antioxidant, anti-inflammatory, and intestinal protective properties of and Georgi extracts. Results showed potential health benefits on body weight, intestinal microbiota, and short-chain fatty acid concentrations. Useful for clinical and animal production applications.

Zhang S et al (2024).
Front Microbiol.
PubMed:
38282732

Effects of Berberis vulgaris fruit extract on oxidative stress status in the kidney and liver of diabetic rats.

Research investigated the effects of fruit extract on oxidative stress in diabetic rats. Understanding oxidative stress in diabetes can help us develop strategies for prevention and treatment.

Ahmadi M, Hadjzadeh MA and Rajaei Z (2024).
J Complement Integr Med.
PubMed:
38282343

Network pharmacology and in vitro experimental verification unveil glycyrrhizin from glycyrrhiza glabra alleviates acute pancreatitis via modulation of MAPK and STAT3 signaling pathways.

Glycyrrhiza glabra (liquorice) might have therapeutic effects in treating acute pancreatitis by interacting with the protein MAPK3, according to computational biology methods and in vitro experiments.

Zhang R et al (2024).
BMC Complement Med Ther.
PubMed:
38280993

Piperlongumine inhibits antioxidant enzymes, increases ROS levels, induces DNA damage and G2/M cell cycle arrest in breast cell lines.

Piperlongumine (PLN) shows potential as an anticancer agent. It increases ROS levels and DNA damage, inhibits antioxidant enzymes, and induces genotoxicity. It inhibits DDR proteins, leading to cell death in non-tumor cells and reduced cell viability in breast cancer cells.

Baranoski A et al (2024).
J Toxicol Environ Health A.
PubMed:
38279841

Antioxidant, AChE inhibitory, and anticancer effects of Verbascum thapsus extract.

In this study, the researchers investigated the biological functions of Verbascum thapsus methanol extract. They used chromatography and spectrometry to analyze its composition, and tested its antioxidant capacity and cytotoxicity on different cell lines. The extract showed low antioxidant activity but inhibited acetylcholinesterase enzyme.

Zhang N et al (2023).
Cell Mol Biol (Noisy-le-grand).
PubMed:
38279434