Evaluation of phytochemical, antibacterial, thrombolytic, anti-inflammatory, and cytotoxicity profile of Achyranthes aspera aerial part extracts.

Achyranthes aspera extracts (ME-E and AQ-E) were analyzed for phytochemicals, antibacterial, thrombolytic, anti-inflammatory, and cytotoxicity activities. ME-E exhibited higher phytochemicals, superior antibacterial and thrombolytic activities, moderate anti-inflammatory activity, and dose-dependent cytotoxicity, suggesting potential biomedical applications.

Ha HA et al (2023).

Environ Res.

DOI:

10.1016/j.envres.2023.117802

PubMed:

38043891

Combined passivators regulate physiological, antioxidant potential and metals accumulation in potato grown in metals contaminated soil.

Wang H et al (2024).

Sci Total Environ.

DOI:

10.1016/j.scitotenv.2023.168956

PubMed:

38043817

Bruceine D suppresses CAF-promoted TNBC metastasis under TNF-α stimulation by inhibiting Notch1-Jagged1/NF-κB(p65) signaling.

TNBC has limited treatment options and poor prognosis. CAFs in the tumor microenvironment contribute to metastasis. Developing therapies targeting TNF-α and other key factors could improve outcomes for TNBC patients.

Chen H et al (2023).

Phytomedicine.

DOI:

10.1016/j.phymed.2023.154928

PubMed:

38043386

Inhibition of Ca(2+)-permeable TRPV3 and inflammatory cytokine release by honokiol and magnolol in human epidermal keratinocytes.

Thi HD et al (2024).

Biochem Biophys Res Commun.

DOI:

10.1016/j.bbrc.2023.149332

PubMed:

38043155

Zinc oxide nanoparticles alleviate chromium-induced oxidative stress by modulating physio-biochemical aspects and organic acids in chickpea (Cicer arietinum L.).

Researchers investigated the effects of zinc oxide nanoparticles (ZnO-NPs) on alleviating chromium (Cr) stress in chickpea plants. ZnO-NP application improved plant growth, reduced Cr accumulation, and minimized oxidative stress. These findings suggest that ZnO-NPs could be used for sustainable agricultural development.

Singh D et al (2023).

Plant Physiol Biochem.

DOI:

10.1016/j.plaphy.2023.108166

PubMed:

38039586

Six new coumarins from the roots of Toddalia asiatica and their anti-inflammatory activities.

Scientists discovered six new compounds, toddasirins A-F, from Toddalia asiatica roots. The compounds were structurally elucidated and assessed for anti-inflammatory activity. Compounds 1-3 and 6 exhibited significant inhibition of nitric oxide (NO) production in RAW 264.7 cells induced by lipopolysaccharide.

He H et al (2023).

Chin J Nat Med.

DOI:

10.1016/S1875-5364(23)60480-7

PubMed:

38035940

The extract from Portulaca oleracea L. rehabilitates skin photoaging via adjusting miR-138-5p/Sirt1-mediated inflammation and oxidative stress.

Purslane extract protects against skin aging caused by UV radiation by reducing oxidative damage and inflammation. It regulates miR-138-5p/Sirt1 signaling, making it a potential natural product for skin care.

Qu L, Wang F and Ma X (2023).

Heliyon.

DOI:

10.1016/j.heliyon.2023.e21955

PubMed:

38034793

The effects of titanium dioxide (TiO(2)) nanoparticles on physiological, biochemical, and antioxidant properties of Vitex plant (Vitex agnus - Castus L).

Spraying titanium dioxide nanoparticles on plants improved root and shoot growth but reduced leaf weight. It also increased chlorophyll levels and antioxidant enzyme activity without affecting proline and soluble protein content, suggesting potential benefits for plant growth and biochemical properties.

Moshirian Farahi SM et al (2023).

Heliyon.

DOI:

10.1016/j.heliyon.2023.e22144

PubMed:

38034643