Immunology Studies

Bio-organic fertilizers promote yield, chemical composition, and antioxidant and antimicrobial activities of essential oil in fennel (Foeniculum vulgare) seeds.

The study found that using a combination of poultry manure, Lactobacillus plantarum, and Lactococcus lactis produced high-quality fennel seed essential oil with strong antimicrobial properties, benefiting industrial use.

Abdelbaky AS et al (2023).
Sci Rep.
PubMed:
37626070

Cannabinoids and standardized cannabis extracts inhibit migration, invasion, and induce apoptosis in MCF-7 cells through FAK/MAPK/Akt/NF-κB signaling.

Suttithumsatid W, Sukketsiri W and Panichayupakaranant P (2023).
Toxicol In Vitro.
PubMed:
37625625

The Immunomodulatory Activity of Punica granatum L. Peel Extract Increases the Lifespan of Mice with Lethal Sepsis.

A study found that a hydroalcoholic crude extract from the peels of L. increased lifespan and reduced bacterial counts in mice with lethal sepsis, suggesting antimicrobial and anti-inflammatory effects. The extract also regulated bacterial load, controlled inflammation, and reduced lung hemorrhage.

de O Trovão L et al (2023).
J Immunol Res.
PubMed:
37621924

Extract of Astragali Radix and Solanum nigrum Linne regulates microglia and macrophage polarization and inhibits the growth and infiltration of C6 glioblastoma.

The researchers investigated the effects of Astragali Radix and Solanum nigrum L. on the polarization of glioma-associated microglia/macrophages (GAMs). Understanding their roles and mechanisms could be useful in treating glioma, a type of brain tumor.

Shen M et al (2023).
J Ethnopharmacol.
PubMed:
37619857

Protease inhibitors characterisation by SDS-PAGE and MALDI-TOF from Alocasia macrorrhizos and their modulation of macrophage immune-inflammatory properties.

This study extracted protease inhibitors from a medicinal plant, identified their properties, and assessed their effects on immune response and cell viability. The results suggest potential immunomodulatory properties without harming cells.

Cordeiro IH et al (2023).
Nat Prod Res.
PubMed:
37615635

Analytical determination, antioxidant and anti-inflammatory activities of Bhamrung-Lohit a traditional Thai medicine.

Researchers studied traditional Thai medicine BRL, assessing its antioxidant and anti-inflammatory properties and developing a new analytical method. Results provide health benefits insights and a reliable analysis method.

Panchakul C et al (2023).
Res Pharm Sci.
PubMed:
37614616

Hippophae rhamnoides L. leaf extracts alleviate diabetic nephropathy via attenuation of advanced glycation end product-induced oxidative stress in db/db mice.

The study found that sea buckthorn leaf extract (SBL) reduced kidney damage in diabetic mice by decreasing the accumulation of advanced glycation end products (AGEs) and oxidative stress. This suggests that SBL could be a potential treatment for diabetic renal complications.

Gu MJ et al (2023).
Food Funct.
PubMed:
37614189