Separation of antioxidant-rich Alternanthera Sessilis Red extracts by Sephadex LH-20 and identification of polyphenols using HPLC-QToF-MS/MS.
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- Chem Biodivers.
- PubMed:
- 37278124
Propolis, a honeybee product, is gaining attention as a potential antioxidant. Reactive oxygen species (ROS) are harmful to cells and are associated with diseases like cancer. Propolis has been shown to protect against oxidative stress and has anticancer effects. This research highlights the importance of finding exogenous antioxidants from dietary sources to combat ROS and prevent diseases.
Purple carnation flowers have been found to have the highest antioxidant and anticancer activities compared to other colors. Through a metabolomics analysis, 932 metabolites were identified and categorized, with several flavonoids, organic acids, phenolic acids, and nucleotides found as specific differential metabolites in purple flowers. Further analysis revealed that 6-hydroxykaempferol-3,6--diglucoside, 6-hydroxykaempferol-7--glucoside, quercetin-3--sophoroside, and 2'-deoxyguanosine were the major constituents responsible for the antioxidant and anticancer activities. Additionally, 2'-deoxyguanosine showed effective antiproliferative activity against certain cancer cells, and its combination with other compounds further enhanced its antitumor activity. These findings expand our knowledge of carnation's phytochemical composition and offer potential for improving the quality of carnation flowers.
In a study, two extracts from fruits of A and C plants reduced weight and adipose tissue in obese rats and improved metabolic and biochemical markers. These extracts have potential for preventing and treating obesity.