Immunology Studies

Effects of okra (Abelmoschus esculentus L.) leaves, fruits and seeds extracts on European sea bass (Dicentrarchus labrax) leukocytes, and their cytotoxic, bactericidal and antioxidant properties.

Guebebia S et al (2023).
Fish Shellfish Immunol.
PubMed:
37187214

Promising effect of Geranium robertianum L. leaves and Aloe vera gel powder on Aspirin(®)-induced gastric ulcers in Wistar rats: anxiolytic behavioural effect, antioxidant activity, and protective pathways.

The effectiveness of traditional drugs for gastric ulcers (GU) is limited, so researchers looked at natural remedies such as Aloe vera and Geranium robertianum. They assessed their ability to protect against Aspirin®-induced GU in rats. The results suggest that these herbal extracts may be promising alternatives for the treatment of GU.

Bawish BM et al (2023).
Inflammopharmacology.
PubMed:
37184667

Antioxidant and anticancer potential of ethyl acetate extract of bark and flower of Tecoma stans (Linn) and In Silico studies on phytoligands against Bcl 2 and VEGFR2 factors.

A study evaluated the antioxidant and anticancer properties of Tecoma stans extracts. The ethyl acetate extract contained the most valuable phytochemicals, particularly flavonoids. Purified flavonoid fractions were confirmed to be enriched. The ethyl acetate extract exhibited high antioxidant activity and dose-dependent cytotoxicity against breast cancer cells. Analysis identified 10 medicinal flavonoids, with 3,5-O-dicaffeoylquinic acid and Isorhamnetin-3-O-rutinoside showing potential interactions with Bcl 2 and VEGFR2, respectively. These findings suggest that T. stans extracts have significant medicinal potential as antioxidant and anticancer agents, pending further animal studies.

Narayanan M et al (2023).
Environ Res.
PubMed:
37182829