Role of NADPH Oxidase-Derived ROS-Mediated IL-6/STAT3 and MAPK/NF-κB Signaling Pathways in Protective Effect of Corilagin against Acetaminophen-Induced Liver Injury in Mice.
- Liu FC et al (2023).
- Biology (Basel).
- PubMed:
- 36829609
Researchers isolated Sarglamides A-E from a plant and found that compounds - and - have unique structures. They proposed possible pathways for their creation and found that compounds - can reduce inflammation.
An herbal medicine, Houttuyniae Herba (HH), traditionally used to treat various ailments, has been found to protect neurons and regulate dysfunction in Alzheimer's disease (AD) models. Administered to transgenic mice, HH reduced amyloid-β accumulation and improved memory impairment. In vitro, HH inhibited amyloid-β aggregation and increased alpha-secretase expression. With anti-neuroinflammatory effects, HH reduced glial activation and increased synaptophysin expression. HH may be a promising herbal drug for AD patients in need of multiple improvements.