Structural properties and in vitro and in vivo immunomodulatory activity of an arabinofuranan from the fruits of Akebia quinata.

Wang H et al (2021).

Carbohydr Polym.

DOI:

10.1016/j.carbpol.2020.117521

PubMed:

33483042

Tinospora Cordifolia: A review of its immunomodulatory properties.

Yates CR, Bruno EJ and Yates MED (2022).

J Diet Suppl.

DOI:

10.1080/19390211.2021.1873214

PubMed:

33480818

Analyzing the Carotenoid Composition of Melilot (Melilotus officinalis (L.) Pall.) Extracts and the Effects of Isolated (All-E)-lutein-5,6-epoxide on Primary Sensory Neurons and Macrophages.

Scientists have investigated the carotenoid content of Meliloti herba, a medicinal plant with anti-inflammatory effects. Using high performance liquid chromatography (HPLC) and column liquid chromatography (CLC), they isolated and identified the main carotenoid as (all-)-lutein 5,6-epoxide and tested its effects on primary sensory neurons and macrophages involved in inflammation. Results showed that lutein 5,6-epoxide reduced the activation of primary sensory neurons and decreased the release of IL-1β from macrophages. This suggests that lutein 5,6-epoxide could be used as an analgesic and anti-inflammatory treatment.

Horváth G et al (2021).

Molecules.

DOI:

10.3390/molecules26020503

PubMed:

33477841

Syzygium cumini(L.),Skeels fruit extracts: In vitro and in vivo anti-inflammatory properties.

Qamar M et al (2021).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2021.113805

PubMed:

33465442

Anemoside B4 ameliorates TNBS-induced colitis through S100A9/MAPK/NF-κB signaling pathway.

Zhang Y et al (2021).

Chin Med.

DOI:

10.1186/s13020-020-00410-1

PubMed:

33461587

Inhibition effect of Caragana sinica root extracts on Osteoarthritis through MAPKs, NF-κB signaling pathway.

Min GY et al (2021).

Int J Med Sci.

DOI:

10.7150/ijms.52330

PubMed:

33456343

Myristica fragrans promotes ABCA1 expression and cholesterol efflux in THP-1-derived macrophages.

Liu S et al (2021).

Acta Biochim Biophys Sin (Shanghai).

DOI:

10.1093/abbs/gmaa146

PubMed:

33434281

Pergularia daemia alters epileptogenesis and attenuates cognitive impairment in kainate-treated mice: Insight into anti-inflammatory mechanisms.

Researchers investigated the potential anti-inflammatory effects of Pergularia daemia in temporal lobe epilepsy, a drug-resistant form of epilepsy. P. daemia is traditionally used in Cameroon to treat various ailments. There are currently no scientific reports on its anti-inflammatory activity during epileptogenesis. The study found that P. daemia extract reduced inflammation and may have antiepileptic effects. This suggests that P. daemia could be a potential source of new antiepileptic drugs and warrants further investigation.

Kavaye Kandeda A et al (2021).

Epilepsy Behav.

DOI:

10.1016/j.yebeh.2020.107707

PubMed:

33429138