Neuroscience Studies

Cannabidiol and Neurodegeneration: From Molecular Mechanisms to Clinical Benefits.

Researchers studied the role of cannabidiol (CBD) in treating neurodegenerative disorders through its antioxidant, anti-inflammatory, and neuroprotective properties. CBD shows promise in inhibiting protein aggregation, free radicals, and neuroinflammation, making it a potential therapeutic option for conditions like Alzheimer's and Parkinson's.

Jha SK et al (2024).
Ageing Res Rev.
PubMed:
38969143

Hop (Humulus lupulus L.) extract reverts glycaemic imbalance and cognitive impairment in an animal model of obesity.

Researchers found that hop bitter acids from hops improved lipid and carbohydrate metabolism in obese mice, stabilizing glycemia levels and weight gain while enhancing antioxidant capacity and brain health. This suggests potential benefits for managing obesity-related complications and cognitive decline.

Alves MDR et al (2024).
Food Funct.
PubMed:
38961720

The remarkable impact of Opuntia Ficus Indica fruit administration on metabolic syndrome: Correlations between cognitive functions, oxidative stress and lipid dysmetabolism in the high-fat, diet-fed rat model.

OFIF, a potential nutraceutical, shows promise in addressing oxyinflammatory-based diseases at both peripheral and central levels. It may mitigate Metabolic Syndrome risks and improve cognitive function in key brain regions.

Di Majo D et al (2024).
Biomed Pharmacother.
PubMed:
38959603

Comprehensive study on pharmacognostic, pharmacological, and toxicological features of Ficus racemosa in Alzheimer's disease using GC-MS and molecular docking analyses.

Researchers investigated potential therapeutic strategies for Alzheimer's disease due to its high prevalence and lack of cure.Understanding these strategies is crucial for developing effective treatments for the millions affected worldwide.

Rani A et al (2024).
Toxicol Res (Camb).
PubMed:
38957785

Quaternity method for integrated screening, separation, extraction optimization, and bioactivity evaluation of acetylcholinesterase inhibitors from Sophora flavescens Aiton.

Researchers studied Sophora flavescens for potential anti-AD effects due to its compounds. Care because it may lead to new Alzheimer's treatments.

Zhang Y et al (2024).
Phytochem Anal.
PubMed:
38957046

Neolignans in Magnolia officinalis as natural anti-Alzheimer's disease agents: A systematic review.

Researchers studied the effects of Magnolia officinalis on various health conditions. Active ingredients show potential for antibacterial, anti-tumor, anti-inflammatory, antioxidant, anti-aging, and anti-Alzheimer's effects. Promising for future treatments.

Li N et al (2024).
Ageing Res Rev.
PubMed:
38955265

Effect of saponins in Panax notoginseng (Burkill) F. H. Chen on the steroid hormone levels in the chronic unpredictable mild stress model of depression in rats.

Study found that ginsenoside Rg1 and PNS from plant relieved depression symptoms in rats. Precise LC-ESI-MS/MS analysis showed positive effects on behavior and hormone levels. Potential antidepressant for humans.

Nguyen Van K et al (2024).
Nat Prod Res.
PubMed:
38949646

Prevention of Chronic Diabetic Neuropathy and Diabetes-Associated Cognitive Impairment Using Medicinal Herbs (Cassia Angustifolia and Nigella Sativa).

Nodal regions in the nervous system are vulnerable to diabetes. Administering NS and CA to hyperglycemic mice improved memory, myelin loss, and synaptic function, suggesting potential benefits for diabetic patients.

Khan M et al (2024).
Yale J Biol Med.
PubMed:
38947105