Neuroscience Studies

Ficus platyphylla alleviates seizure severity and neurobehavioral comorbidities in pentylenetetrazole-kindled rats via modulation of oxidative stress.

Researchers studied the effects of Ficus platyphylla extract on seizure severity, cell degeneration, and behavioral changes in PTZ-kindled rats. FP reduced these effects, suggesting potential treatment for epilepsy and neuropsychiatric comorbidities.

Chindo BA et al (2024).
Brain Res.
PubMed:
38729331

Hippocampal D1-like dopamine receptor as a novel target for the effect of cannabidiol on extinction and reinstatement of methamphetamine-induced CPP.

CBD interacts with D1-like dopamine receptors in the hippocampus to reduce METH-seeking behavior. This suggests CBD may be a potential treatment for methamphetamine addiction.

Farrokhi AM et al (2024).
Prog Neuropsychopharmacol Biol Psychiatry.
PubMed:
38729234

Hypoglycemic, anti-inflammatory, and neuroprotective potentials of crude methanolic extract from Acacia nilotica L. - results of an in vitro study.

Babul plant extract has potential as a natural remedy for diabetes, inflammation, and neuroprotection. It inhibits key enzymes and shows promise in reducing inflammatory markers. Further research is needed for validation.

Rauf A et al (2024).
Food Sci Nutr.
PubMed:
38726429

Polysaccharide extracted from Sarcandra glabra residue attenuate cognitive impairment by regulating gut microbiota in diabetic mice.

SERP from Sarcandra glabra improves cognitive function in diabetic encephalopathy by regulating gut microbiota, lipid metabolism, and butyric acid levels. Promising treatment option targeting "microbiota-gut-brain axis".

Ye M et al (2024).
Int J Biol Macromol.
PubMed:
38719002

LC-qTOF-MS/MS phytochemical profiling of Tabebuia impetiginosa (Mart. Ex DC.) Standl. leaf and assessment of its neuroprotective potential in rats.

Researchers studied Tabebuia impetiginosa for its traditional uses of memory enhancement and CNS stimulation, providing potential insight for neurological research and drug development.

Khaled N et al (2024).
J Ethnopharmacol.
PubMed:
38705428

Alkaloids in Uncaria rhynchophylla improves AD pathology by restraining CD4(+) T cell-mediated neuroinflammation via inhibition of glycolysis in APP/PS1 mice.

UR and URA from Uncaria rhynchophylla show neuroprotective effects for Alzheimer's and other CNS diseases. Mechanisms not fully understood.Important for potential medical treatments.

Kuang Y et al (2024).
J Ethnopharmacol.
PubMed:
38703874

Antidepressant-Like Effects of Cinnamomum verum on Open-Space Forced Swim-Induced Depression in Mice.

Researchers tested cinnamon's antidepressant effects on mice with induced depression. Cinnamon decreased immobility time in a forced swim test, showing potential as a natural antidepressant. Consider cinnamon for its anti-depressant qualities.

Yusha'u Y, Aminu Hanafi A and Muhammad Adam U (2023).
Niger J Physiol Sci.
PubMed:
38696678

Effect of Kencur (Kaempferia galanga L.) Ethanolic Extract Treatment on Cerebral Caspase-3 Expression in Traumatic Brain Injury Rat Models.

Kencur extract may help prevent cell death in traumatic brain injury by inhibiting caspase-3, potentially reducing oxidative stress and inflammation.

Suryo AP et al (2024).
Malays J Med Sci.
PubMed:
38694581