Investigating the effects of Thymus vulgaris essential oil, Allium cepa extract, and their active compounds (thymol and quercetin) on expression profile of genes related to Alzheimer's disease in PC12 model cell.

Foroughi S et al (2024).

Brain Res.

DOI:

10.1016/j.brainres.2024.148966

PubMed:

38688382

Effect of Dl-3-n-Butylphthalide on olfaction in rotenone-induced Parkinson's rats.

Researchers studied the effect of synthetic compound NBP on PD rats with od dysfunction. Results may provide insights into PD mechanism and potential treatment for olfactory dysfunction.

Wang J et al (2024).

Front Neurol.

DOI:

10.3389/fneur.2024.1367973

PubMed:

38685946

Terpenoids from Alpinia galanga and their acetylcholinesterase inhibitory activity.

Researchers isolated new compounds from Zingiberaceae seeds, determining their structures and configurations. Some showed acetylcholinesterase inhibitory activity, potentially useful for neurological treatments.

Zhou B et al (2024).

Nat Prod Res.

DOI:

10.1080/14786419.2024.2346269

PubMed:

38683975

Ecdysterone improves oxidative damage induced by acute ischemic stroke via inhibiting ferroptosis in neurons through ACSL4.

Researchers studied the effects of Ecdysterone from Achyranthes bidentata Blume on acute ischemic stroke (AIS). EDS shows antioxidant and anti-cerebral hypoxia properties, potentially improving AIS outcomes. This research may lead to new therapies for stroke patients.

Sun J et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.118204

PubMed:

38679397

Pharmacokinetic analysis of antiviral drug ritonavir across the blood-brain barrier and its interaction with Scutellaria baicalensis using multisite microdialysis in rats.

TL;DR: Interaction between ritonavir and S. baicalensis boosts flavones in blood/brain, helping treat SARS-CoV-2. Important for understanding herb-drug interactions in COVID-19 treatment.

Sun CK et al (2024).

J Pharm Biomed Anal.

DOI:

10.1016/j.jpba.2024.116162

PubMed:

38678857

A novel isoquinoline alkaloid HJ-69 isolated from Zanthoxylum bungeanum attenuates inflammatory pain by inhibiting voltage-gated sodium and potassium channels.

Scientists studied isoquinoline alkaloids in Z. bungeanum for potential medicinal benefits. This plant has traditional use for arthritis and toothache in Asia. Research may lead to new treatments.

Wang L et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.118218

PubMed:

38677570

The Repellent Capacity against Sitophilus zeamais (Coleoptera: Curculionidae) and In Vitro Inhibition of the Acetylcholinesterase Enzyme of 11 Essential Oils from Six Plants of the Caribbean Region of Colombia.

Eleven essential oils from Colombian plants repelled and had varying effects on AChE. Some oils were as effective as a commercial pesticide. Active compounds were identified. Use for natural pest control.

Muñoz-Acevedo A et al (2024).

Molecules.

DOI:

10.3390/molecules29081753

PubMed:

38675573

Effects of Green and Gold Kiwifruit Varieties on Antioxidant Neuroprotective Potential in Pigs as a Model for Human Adults.

Kiwifruit boosts antioxidant capacity in pigs' brains & plasma. Green KF increases FRAP, gold KF raises ascorbate. Polyphenols play a role in brain health. Eat kiwifruit for brain protection.

Kanon AP et al (2024).

Nutrients.

DOI:

10.3390/nu16081097

PubMed:

38674790