Neuroscience Studies

Hydroxysafflor Yellow A Exerts Neuroprotective Effects by Inhibiting Protein Carbonyl Formation in Cerebral Ischemia-Reperfusion Injury.

HSYA from Carthamus tinctorius protects against cerebral ischemia-reperfusion injury by reducing protein carbonylation, improving neurological function, and enhancing antioxidant capacity through ONOO- scavenging and suppressing protein oxidation.

Zhao R et al (2024).
Altern Ther Health Med.
PubMed:
38430158

Intermittent fasting along with hydroalcoholic extract of Centella-asiatica ameliorates sub-acute hypoxia-induced ischemic stroke in adult zebrafish.

Study shows Centella-Asiatica extract and intermittent fasting protect brain from hypoxia-induced damage in zebrafish. Benefits include antioxidant, anti-inflammatory, and neuroprotective effects, along with improved mitochondrial function. Useful for stroke prevention research and potential clinical applications.

Bindal P et al (2024).
Comp Biochem Physiol C Toxicol Pharmacol.
PubMed:
38428624

The efficacy and safety of Chinese herbal medicine for mild cognitive impairment: a systematic review and meta-analysis of randomized placebo-controlled trials.

TL;DR: Chinese herbal medicine (CHM) shows potential in improving cognitive function for mild cognitive impairment (MCI) patients, supported by moderate evidence. Most studies had some bias concerns, but CHM was generally safe with common gastrointestinal side effects.

Liu L et al (2024).
Front Pharmacol.
PubMed:
38425647

Baseline symptom severity and efficacy of Silexan in patients with anxiety disorders: A symptom-based, patient-level analysis of randomized, placebo-controlled trials.

Silexan, an essential oil, is effective in treating anxiety disorders, especially in early stages. Baseline severity influences treatment outcome, with more severe symptoms showing greater improvement. Helpful for mild to moderate cases.

Dold M et al (2024).
Eur Psychiatry.
PubMed:
38425206

Therapeutic potential of CB(1)R activation by Qingyangshen glycoside M1 for seizure relief.

Researchers investigated the potential anti-epileptic properties of glycosides from Qingyangshen (QYS), a traditional medicine. Understanding the mechanisms of action could lead to new treatments for neurological disorders.

Mu X et al (2024).
J Ethnopharmacol.
PubMed:
38423411

Pharmacodynamics and mechanism of Erigeron breviscapus granules in the treatment of ischemic stroke in mice by regulating sphingolipid metabolism based on metabolomics.

They studied how Erigeron breviscapus (EB) granules treat ischemic stroke (IS) by examining its metabolic effects. Understanding the mechanism can lead to better treatment options for IS.

Liu C et al (2024).
J Pharm Biomed Anal.
PubMed:
38422673

Polygalacic acid attenuates cognitive impairment by regulating inflammation through PPARγ/NF-κB signaling pathway.

Researchers studied how polygalacic acid from Polygala tenuifolia treats Alzheimer's disease. Understanding its mechanism can lead to new treatments for AD.

Zhao T and Jia J (2024).
CNS Neurosci Ther.
PubMed:
38421141

Mating strategies of Vitex negundo L. var. heterophylla (Franch.) Rehder (Lamiaceae): A mixed mating system with inbreeding depression.

Scientists studied the reproductive characteristics of var. to understand its mating system and pollination patterns. Results show a mixed mating system dominated by outcrossing, with low seed germination in inbred lines. This research is crucial for conservation of plant diversity and ecosystem protection.

Zhang Q et al (2024).
Ecol Evol.
PubMed:
38414571