Neuroscience Studies

Molecular interplay between phytoconstituents of Ficus Racemosa and neurodegenerative diseases.

Researchers investigated the potential therapeutic effects of phytoconstituents from the plant Ficus racemosa on neurodegenerative diseases. They found that these compounds have promising interactions with pathological pathways and could be valuable for treating these diseases, suggesting a path for future research and treatment development.

Neuroscience Ficus racemosa
Rani A et al (2024).
Eur J Neurosci.
DOI:
10.1111/ejn.16250
PubMed:
38217338

Efficacy and safety of traditional plant-based medicines for preventing chronic oxaliplatin-induced peripheral neurotoxicity in patients with colorectal cancer: A systematic review and meta-analysis with core herb contribution.

Researchers studied the use of traditional plant-based medicines to prevent nerve damage caused by chemotherapy. Results are unclear due to different medicine combinations and lack of understanding of their mechanisms.

CancerGastroenterologyNeuroscience Atractylodes macrocephalaCodonopsis pilosula
Han J et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.117735
PubMed:
38211824

Assessing the potential of Psidium guajava derived phytoconstituents as anticholinesterase inhibitor to combat Alzheimer's disease: an in-silico and in-vitro approach.

Researchers discovered Fluspirilene, a compound from a fruit extract, with high potential as an Alzheimer's disease treatment by inhibiting acetylcholinesterase. This highlights the significance of natural sources in drug discovery for Alzheimer's treatment.

Neuroscience Psidium guajava
Bhattacharya K, Bhattacharjee A and Chakraborty M (2024).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2024.2301930
PubMed:
38205777

Correction: Gardenia jasminoides J. Ellis extract alleviated white matter damage through promoting the differentiation of oligodendrocyte precursor cells via suppressing neuroinflammation.

The study showed that an extract could protect and repair white matter damage in the brain. This is important because it promotes the differentiation of brain cells and reduces inflammation, which can have implications for treating neurological conditions.

Neuroscience Gardenia jasminoides
Zang C et al (2024).
Food Funct.
DOI:
10.1039/d3fo90113k
PubMed:
38205631

Total Antioxidant Potential, Total Phenolic Profile and Cytotoxic Activity Against Brain Cancer: Melocan and Galdirik(§).

Researchers investigated the antioxidant and cytotoxic effects of Melocan and galdirik, two traditional ingredients of the Black Sea region. This study could provide valuable insights for new alternative treatments for brain cancer.

CancerImmunologyNeurosciencePhytochemistry Smilax excelsaTrachystemon orientalis
Al Yassine D et al (2023).
Food Technol Biotechnol.
DOI:
10.17113/ftb.61.04.23.8071
PubMed:
38205056

Targeting inflammation and oxidative stress for protection against ischemic brain injury in rats using cupressuflavone.

This study shows that cupressuflavone (CUP), a bioflavonoid found in Abhal plants, has neuroprotective effects on brain ischemia/reperfusion (IR) injury in rats. CUP reduces neurological deficits, inflammation, and oxidative stress, potentially making it a promising treatment for stroke.

ImmunologyNeuroscience Juniperus sabina
Albaqami FF et al (2024).
Saudi Pharm J.
DOI:
10.1016/j.jsps.2023.101933
PubMed:
38204594

Protective Effects of Sophoraflavanone G by Inhibiting TNF-α-Induced MMP-9-Mediated Events in Brain Microvascular Endothelial Cells.

Sophoraflavanone G (SG) inhibits MMP-9 expression and protects brain cells by maintaining tight junctions, potentially offering neuroprotection.

Neuroscience Sophora flavescens
Lee TH et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms25010283
PubMed:
38203454

Antioxidant Systems and Quality in Sweet Cherries Are Improved by Preharvest GABA Treatments Leading to Delay Postharvest Senescence.

GABA treatment at 50 mM concentration improves fruit quality, extends storage period by 2 weeks, enhances antioxidant properties, and increases bioactive compound content in sweet cherries.

ImmunologyNeuroscience Prunus avium
Carrión-Antolí A et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms25010260
PubMed:
38203428
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