Safranal, an active compound in saffron, reduces brain damage after ischemic stroke (IS) by reducing oxidative stress. It promotes neuron survival, stimulates neurogenesis, induces angiogenesis, and increases SIRT1 expression. Silencing SIRT1 reverses these effects. Safranal shows promise for restoring neural function after IS.
Study investigated effects of geniposide (GE) on depression-like behavior in prenatal stress-induced male mice. GE had antidepressant effects and may be a potential treatment for prenatal stress-related mental health issues in offspring.
Researchers investigated the neuroprotective effects of a formulation containing Bacopa monnieri leaves, Nigella sativa, and Curcuma longa rhizome seeds. This formulation may help protect against oxidative stress and cell death induced by diclofenac, a common anti-inflammatory drug.
CBD from Cannabis sativa has potential for delaying aging and treating Alzheimer's disease (AD). This article explores the correlation between cellular senescence, aging, and AD, and summarizes the role and mechanisms of CBD in preventing aging and treating AD.
Melissa officinalis extract (MEE) protected against brain damage in rats with hypothyroidism and/or exposure to radiation by reducing oxidative stress and endoplasmic reticulum stress. MEE also prevented the overexpression of genes associated with apoptosis and improved neuronal protection.
Mediterranean saltbush contains beneficial compounds like phenols and flavonoids, which have antioxidant properties. These compounds also have potential health benefits against diabetes and acetylcholinesterase-related conditions. Enzyme activities are linked to the presence of terpenes, sterols, saponins, coumarins, and carotenoids.
O. corniculata has anti-inflammatory and antioxidant properties and is used to manage epilepsy, gastric disorders, and neurodegenerative diseases. It could potentially be beneficial in treating Alzheimer's disease due to its ability to combat neuroinflammation and oxidative stress.
Researchers investigated the potential of taxus chinensis fruit (TCF) in treating Alzheimer's disease (AD). They identified the constituents and targets associated with AD. Relevant for potential AD treatment.