Neuroscience Studies

Neuroprotective Effect of Solid Lipid Nanoparticles Loaded with Lepidium sativum (L.) Seed Bioactive Components Enhance Bioavailability and Wnt/β-Catenin/Camk-II Signaling Cascade in SH-SY5Y Neuroblastoma Cells.

Solid lipid nanoparticles (SLNps) loaded with seed extract show potential as a therapeutic approach for Alzheimer's disease by increasing bioavailability and efficacy in preventing oxidative stress-induced neurodegeneration. LS-SLNps exhibit neuroprotective effects, boost cell proliferation, and stimulate nerve cell growth factor expression.

Neuroscience Lepidium sativum
Al-Saran N et al (2024).
Nanomaterials (Basel).
DOI:
10.3390/nano14020199
PubMed:
38251163

The Standardized Extract of Centella asiatica and Its Fractions Exert Antioxidative and Anti-Neuroinflammatory Effects on Microglial Cells and Regulate the Nrf2/HO-1 Signaling Pathway.

Researchers investigated the bioactivity of triterpenes in the ethanolic extract of Centella asiatica (SECA) and found potential benefits for treating Alzheimer's disease by reducing neuroinflammation and oxidative stress.

Neuroscience Centella asiatica
Hambali A et al (2024).
J Alzheimers Dis.
DOI:
10.3233/JAD-230875
PubMed:
38250772

Green Synthesis of Cerium Oxide Nanoparticles, Characterization, and Their Neuroprotective Effect on Hydrogen Peroxide-Induced Oxidative Injury in Human Neuroblastoma (SH-SY5Y) Cell Line.

Scientists synthesized cerium oxide nanoparticles (CeONPs) from () leaf extract, known for neuroprotective properties. CeONPs showed antioxidant activity and protected human neuroblastoma cells from oxidative stress-induced damage and apoptosis. CeONPs could be valuable in treating neurodegenerative disorders.

Neuroscience Centella asiatica
Mamatha MG et al (2024).
ACS Omega.
DOI:
10.1021/acsomega.3c07505
PubMed:
38250384

Polyamines in Edible and Medicinal Fungi from Serbia: A Novel Perspective on Neuroprotective Properties.

Certain fungi from Serbia have neuroprotective and antioxidant properties due to polysaccharides and phenolic compounds. Some fungi exhibit strong anti-AChE activity possibly related to high polyamine levels, requiring further study.

Neuroscience Ganoderma applanatum
Rašeta M et al (2023).
J Fungi (Basel).
DOI:
10.3390/jof10010021
PubMed:
38248931

Hemerocallis citrina Baroni ameliorates chronic sleep deprivation-induced cognitive deficits and depressive-like behaviours in mice.

Hemerocallis citrina extract (HCE) was given to sleep-deprived mice. HCE improved cognitive function, reduced depression-like behaviors, and decreased inflammation in the hippocampus. HCE may be useful in preventing and treating cognitive decline and depression caused by sleep deprivation.

Neuroscience Hemerocallis citrina
Jiang N et al (2024).
Life Sci Space Res (Amst).
DOI:
10.1016/j.lssr.2023.04.001
PubMed:
38245346

Comparing the effects of rosemary aromatherapy and music therapy on anxiety levels in patients undergoing general surgery: A randomized controlled clinical trial.

Study compared inhalation aromatherapy using rosemary essential oil and music therapy in reducing anxiety levels of general surgery patients. Results may help in managing preoperative anxiety and improving patient outcomes.

Neuroscience Rosmarinus officinalis
Sayadi Mank-Halati M et al (2024).
Explore (NY).
DOI:
10.1016/j.explore.2024.01.002
PubMed:
38242798

Essential oil of Pterocarpus santalinus L. alleviates behavioral impairments in social defeat stress-exposed mice by regulating neurotransmission and neuroinflammation.

Scientists investigated the antidepressant effects of Pterocarpus santalinus L. essential oil (PSEO) in socially stressed mice. The study aims to discover the mechanisms and components of PSEO and its potential use in treating depression.

NeurosciencePhytochemistry Pterocarpus santalinus
Nguyen LTH et al (2024).
Biomed Pharmacother.
DOI:
10.1016/j.biopha.2024.116164
PubMed:
38242042

Identification and function analysis of GABA branch three gene families in the cotton related to abiotic stresses.

GABA genes in cotton plants linked to stress resistance, particularly against salt and high temperatures. GABA protects leaves from damage by increasing enzyme activity and reducing reactive oxygen species.

GeneticsNeuroscience Gossypium barbadenseGossypium hirsutum
Zheng J et al (2024).
BMC Plant Biol.
DOI:
10.1186/s12870-024-04738-w
PubMed:
38238675
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