Neuroscience Studies

Polygala tenuifolia and Acorus tatarinowii in the treatment of Alzheimer's disease: a systematic review and meta-analysis.

Researchers evaluated the clinical efficacy and safety of a combination of two Chinese herbal formulas, PT and AT, for the treatment of Alzheimer's disease. The combination showed potential in improving cognition and functioning without increasing adverse events, but the quality of evidence is low.

Zhang Y et al (2024).
Front Pharmacol.
PubMed:
38283842

Apolar Extracts of St. John's Wort Alleviate the Effects of β-Amyloid Toxicity in Early Alzheimer's Disease.

The study found that an apolar supercritical CO extract of St. John's wort showed better effects against Alzheimer's disease (AD) compared to other extracts. It improved food intake, body weight, and reduced soluble and insoluble Aβ, suggesting it could be a recommended treatment for mild cognitive impairment or early AD.

El Menuawy A et al (2024).
Int J Mol Sci.
PubMed:
38279301

Inhalation of Pelargonium graveolens Essential Oil Alleviates Pain and Related Anxiety and Stress in Patients with Lumbar Spinal Stenosis and Moderate to Severe Pain.

Inhaling geranium essential oil reduced pain, anxiety, and stress in lumbar spinal stenosis patients. It may be a helpful additional therapy for pain and psychological factors.

Seo E et al (2023).
Pharmaceuticals (Basel).
PubMed:
38275987

Inhibition of Seizure-Like Paroxysms and Toxicity Effects of Securidaca longepedunculata Extracts and Constituents in Zebrafish Danio rerio.

Traditional medicinal plants used for epilepsy could provide new antiepileptic drugs. This study found phenolic compounds in the plant that inhibited seizures in zebrafish larvae, as well as potential toxic effects. These findings contribute to the understanding of the plant's medicinal properties and could lead to the development of new drugs.

Moussavi N et al (2024).
ACS Chem Neurosci.
PubMed:
38270158

Exploring the Therapeutic Potential of Phytoconstituents for Addressing Neurodegenerative Disorders.

This article reviews the use of natural compounds like curcumin, wolfberry, ginseng, and Withania somnifera to treat neurodegenerative diseases. These compounds have strong anti-inflammatory and anti-oxidant properties that can prevent neurological dysfunction and improve neuronal function.

Kamboj S et al (2024).
Cent Nerv Syst Agents Med Chem.
PubMed:
38265386

Predicting and optimizing reactive oxygen species metabolism in Punica granatum L. through machine learning: role of exogenous GABA on antioxidant enzyme activity under drought and salinity stress.

This study used machine learning models to predict the effects of gamma-aminobutyric acid (GABA) on plant traits during drought, salinity, and combined stress conditions. These findings could help enhance crop tolerance to stress factors, benefiting food security.

Zarbakhsh S et al (2024).
BMC Plant Biol.
PubMed:
38263036

Nutraceuticals and phytoceuticals in the treatment of schizophrenia: a systematic review and network meta-analysis.

This study assessed nutraceutical/phytoceutical augmentation strategies for schizophrenia. Sarcosine, citicoline, and N-acetylcysteine showed promise in improving symptoms, but more high-quality trials are needed.

Fornaro M et al (2024).
Res Sq.
PubMed:
38260297

Deciphering Neuroprotective Effect of Rosmarinus officinalis L. (syn. Salvia rosmarinus Spenn.) through Preclinical and Clinical Studies.

Rosemary shows neuroprotective properties in studies, inhibiting cholinesterase and modulating dopamine and oxytocin systems. It has antidepressant and anxiolytic effects and may improve memory. More research, including placebo-controlled studies, is needed. Rosemary constituents could have potential as drugs for Alzheimer's disease.

Oresanya IO and Orhan IE (2024).
Curr Drug Targets.
PubMed:
38258779