Study investigates hyperoside from Hypericum perforatum for antidepressant effects. Results will help understand effectiveness for depression treatment.
Celastrol protects neurons by improving mitochondrial function and blocking cell death pathways in ICH-induced secondary brain injury. Targeting EPAC-1 with celastrol shows promise as a therapeutic strategy.
BS drug pair is effective for depression and tumor treatment, but simultaneous targeting mechanism remains unclear. Understanding could lead to new treatment approaches for both conditions.
Berberine may have immunomodulatory effects on T cell subsets and dendritic cells, impacting cytokines involved in multiple sclerosis. Research suggests potential therapeutic benefits for treating MS.
Cannabidiol (CBD) from Cannabis sativa L. shows neuroprotective effects on CNS diseases via interactions with endocannabinoid system and 5-HT receptor, offering potential treatment for epilepsy, Parkinson's, and multiple sclerosis. Further research needed for stronger evidence.
Researchers identified volatile components in different parts of the fern and compared their medicinal properties. Crozier had strong antioxidant activity, while underground parts showed potential for AChE inhibition. Common volatile compounds have various applications in food, cosmetics, and pharmaceuticals.
Study showed L. cv. Sango sprout extract has pain relief properties similar to ketorolac without gastric damage. Works through opioid, serotonin receptors, cAMP/NO-cGMP pathways, and SFN. Consuming could be beneficial for pain relief.
Researchers studied hyperforin's effects on VCI, finding it to have neuroprotective potential. Understanding its molecular mechanisms could lead to new therapeutic approaches for cognitive impairment.