GeoBotanical: Neuroscience Studies

249.

Therapeutic Polymer-Based Cannabidiol Formulation: Tackling Neuroinflammation Associated with Ischemic Events in the Brain.

Researchers developed a synthetic polymer nano-system for delivering CBD to improve its effectiveness in treating neuroinflammation. This system shows promising results in restoring mitochondrial function in cells after ischemic events. Worth considering for preclinical studies.

Neuroscience Cannabis sativa

Chevalier MT et al (2024).; Mol Pharm.
DOI:: 10.1021/acs.molpharmaceut.3c00244
PubMed:: 38412451

250.

Effectiveness of Novel Drug Delivery System using Curcumin in Alzheimer's Disease.

Study investigated natural product curcumin's effectiveness in treating Alzheimer's disease. Curcumin has anti-amyloid & anti-inflammatory properties, but poor bioavailability. Novel formulations improve bioavailability, potential treatment option for AD.

Neuroscience Curcuma longa

Urmila A, Kundlik R and Mathure D (2024).; Cent Nerv Syst Agents Med Chem.
DOI:: 10.2174/0118715249279534240214111155
PubMed:: 38409724

251.

Sophora flavescens alcohol extract ameliorates insomnia and promotes PI3K/AKT/BDNF signaling transduction in insomnia model rats.

This study found that Sophora flavescens extract promotes deep sleep, reduces insomnia symptoms, and activates brain signaling pathways. It could be a potential treatment for insomnia.

Neuroscience Sophora flavescens

Wu Y et al (2024).; Neuroreport.
DOI:: 10.1097/WNR.0000000000001999
PubMed:: 38407863

252.

Investigation of neuroprotective and therapeutic effects of cannabidiol in an acute coronary syndrome model.

Study shows CBD from Cannabis sativa protects brain from I/R injury in heart. Potential neuroprotective and therapeutic benefits. Worth exploring for organ damage prevention.

Neuroscience Cannabis sativa

Dogan Unlu M et al (2024).; Neurosci Lett.
DOI:: 10.1016/j.neulet.2024.137689
PubMed:: 38401641

253.

Treatment with Glycyrrhiza glabra Extract Induces Anxiolytic Effects Associated with Reduced Salt Preference and Changes in Barrier Protein Gene Expression.

GG extract reduced anxiety behavior and salt preference in rats under chronic stress conditions by altering gene expression of barrier proteins in the prefrontal cortex. GG may be a beneficial therapy for depression and anxiety disorders with high aldosterone levels and inflammation.

Genetics Neuroscience Glycyrrhiza glabra

Murck H et al (2024).; Nutrients.
DOI:: 10.3390/nu16040515
PubMed:: 38398838

254.

Levistilide A Exerts a Neuroprotective Effect by Suppressing Glucose Metabolism Reprogramming and Preventing Microglia Polarization Shift: Implications for Parkinson's Disease.

Levistilide A (LA) from Angelica sinensis decreases inflammation in microglia, protects neurons, and modulates glucose metabolism in Parkinson's disease, showing therapeutic promise.

Neuroscience Angelica sinensis

Zhang M et al (2024).; Molecules.
DOI:: 10.3390/molecules29040912
PubMed:: 38398662

255.

Anti-Neuroinflammatory Effects of Adaptogens: A Mini-Review.

Adaptogens are plants that help the body adapt to stress and promote resilience. They have anti-inflammatory effects and may improve conditions in central nervous system disorders. Research aims to understand their benefits on neuroinflammation.

Neuroscience Eleutherococcus senticosus Schisandra chinensis Withania somnifera

Wróbel-Biedrawa D and Podolak I (2024).; Molecules.
DOI:: 10.3390/molecules29040866
PubMed:: 38398618

256.

Baccharis dracunculifolia DC Consumption Improves Nociceptive and Depressive-like Behavior in Rats with Experimental Osteoarthritis.

DC extract from Brazilian plant reversed chronic pain and emotional impairments in osteoarthritic rats. Contains anti-inflammatory compounds, potential for nutraceuticals and functional foods.

Neuroscience Pain Baccharis dracunculifolia

Laranjeira IM et al (2024).; Foods.
DOI:: 10.3390/foods13040535
PubMed:: 38397516