Neuroscience Studies

Exploring potential inhibitors of acetylcholinesterase, lactate dehydrogenases, and glutathione reductase from Hagenia abyssinica (Bruce) J.F. Gmel. based on multi-target ultrafiltration-liquid chromatography-mass spectrometry and molecular docking.

H. Abyssinica has potential antiparasitic compounds. Traditionally used to treat parasitic infections. Important for public health worldwide. More research needed for potential treatments.

Fan M et al (2024).
J Ethnopharmacol.
PubMed:
38763372

Astrocyte modulation in cerebral ischemia-reperfusion injury: A promising therapeutic strategy.

82 drugs targeting astrocytes show promise for treating cerebral ischemia-reperfusion injury, with potential to reduce inflammation, oxidative stress, edema, and more. Traditional Chinese medicines like Salvia miltiorrhiza, Ginkgo, and Ginseng are particularly promising.

Wang Z et al (2024).
Exp Neurol.
PubMed:
38762094

Real-world Chinese herbal medicine for Parkinson's disease: a hospital-based retrospective analysis of electronic medical records.

Chinese medicine therapies show promise in treating Parkinson's disease in controlled settings. However, real-world usage and patient demographics remain unclear. Understanding this can aid in better utilization of these therapies.

Lyu S et al (2024).
Front Aging Neurosci.
PubMed:
38756536

A network pharmacology-based method to explore the therapeutic effect of honokiol on diabetes with comorbid depression in mice.

Honokiol from Magnolia officinalis may help treat diabetes with depression by activating RXR/VDR heterodimer. This could restore autophagy balance and improve neuroplasticity in the hippocampus.

Sun H et al (2024).
Eur J Pharmacol.
PubMed:
38754538

Effects of Passiflora incarnata and Valeriana officinalis in the control of anxiety due to tooth extraction: a randomized controlled clinical trial.

Study tested Valeriana officinalis and Passiflora incarnata for anxiety and discomfort during extraction of two molars. Results can help improve patient experience during dental procedures.

Velasquez ACA et al (2024).
Oral Maxillofac Surg.
PubMed:
38743126

Terminalia chebula attenuates restraint stress-induced memory impairment and synaptic loss in the dentate gyrus of the hippocampus and the basolateral and central nuclei of the amygdala by inhibiting oxidative damage.

Terminalia chebula reduces cognitive abnormalities from chronic stress by improving memory, synaptic density, and antioxidant levels in the brain. This suggests potential neuroprotective effects of Terminalia chebula in stress-induced conditions.

Khazani H et al (2024).
Brain Res Bull.
PubMed:
38734185