Dendrobium Nobile Lindl. Alkaloid Suppresses NLRP3-Mediated Pyroptosis to Alleviate LPS-Induced Neurotoxicity.

Li DD et al (2022).

Front Pharmacol.

DOI:

10.3389/fphar.2022.846541

PubMed:

35586062

Lignans with neuroprotective activity from the fruits of Crataegus pinnatifida.

Xin BS et al (2022).

Fitoterapia.

DOI:

10.1016/j.fitote.2022.105216

PubMed:

35569638

Neuroprotective Potential of Guiera senegalensis (Combretaceae) Leaf Hydroethanolic Extract against Cholinergic System Dysfunctions and Oxidative Stress in Scopolamine-Induced Cognitive Impairment in Zebrafish (Danio rerio).

Damo JLK et al (2022).

Plants (Basel).

DOI:

10.3390/plants11091149

PubMed:

35567150

Erigeron breviscapus (Vant.) Hand-Mazz.: A Promising Natural Neuroprotective Agent for Alzheimer's Disease.

Dong X and Qu S (2022).

Front Pharmacol.

DOI:

10.3389/fphar.2022.877872

PubMed:

35559239

Sirtuins, a key regulator of ageing and age-related neurodegenerative diseases.

Bhatt V and Tiwari AK (2023).

Int J Neurosci.

DOI:

10.1080/00207454.2022.2057849

PubMed:

35549800

Neuroprotective properties of solanum leaves in transgenic Drosophila melanogaster model of Alzheimer's disease.

The study looked at the impact of African eggplant and Black nightshade leaves on Alzheimer's disease. They analyzed behavior, biochemistry, and tissue samples using a mouse model. Results suggest that both vegetables may have some positive effects on delaying Alzheimer's disease progression.

Ogunsuyi OB, Olasehinde TA and Oboh G (2022).

Biomarkers.

DOI:

10.1080/1354750X.2022.2077446

PubMed:

35546534

Modulation of GPCR receptors common to gut inflammatory diseases and neuronal disorders, Alzheimer's and Parkinson's diseases as druggable targets through Withania somnifera bioactives: an in silico study.

The gut microbiota's dysbiosis may lead to neurodegenerative diseases like Alzheimer's and Parkinson's due to increased gut and blood-brain barrier permeability. () is a promising plant for treating neurodegenerative diseases and bowel disorders. The researchers identified five proteins and five best lead compounds after molecular docking analysis and simulation studies, revealing HTR1A and HTR7 proteins with the leads Withanolide E and Withanolide A against them, respectively as the most effective targets. Thus by targeting common potential targets, modulation with bioactive compounds present in can result in effective control of these diseases.

Shukla R et al (2023).

J Biomol Struct Dyn.

DOI:

10.1080/07391102.2022.2068072

PubMed:

35491707

Platycladus orientalis seed extract as a potential triple reuptake MAO inhibitor rescue depression phenotype through restoring monoamine neurotransmitters.

Yan L et al (2022).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2022.115302

PubMed:

35489661