Neuroscience Studies

L-Glutamate treatment alleviates chilling injury of prune (Prunus domestica L.) fruit by regulating ROS homeostasis, GABA shunt, and energy metabolism.

L-Glu treatment reduces chilling injury in prune fruit by enhancing Ca signaling, GABA content, and antioxidant capacity. Optimal concentration is 0.1g/L. Enhances mitochondrial structure and energy levels under cold stress.

Hou Y et al (2024).
Food Chem.
PubMed:
39208637

Polygonatum sibiricum Polysaccharides Alleviate Depressive-like Symptoms in Chronic Restraint Stress-Induced Mice via Microglial Regulation in Prefrontal Cortex.

PSP, a polysaccharide extracted from natural sources, shows potential as an antidepressant by regulating microglial activity and neuroinflammatory pathways in mice under chronic restraint stress. This study highlights the importance of PSP in treating depression.

Yuan ZY et al (2024).
Polymers (Basel).
PubMed:
39204578

Vicia faba L. Pod Valves: A By-Product with High Potential as an Adjuvant in the Treatment of Parkinson's Disease.

Researchers studied lucan broad bean pod valves (BPs) rich in L-dopa and polyphenols for Parkinson's treatment. BP extracts showed higher L-dopa content than seeds, with neuroprotective polyphenols, antioxidants, and no harmful metabolites. BP extracts were more effective than synthetic L-dopa in preventing oxidative stress.

Tesoro C et al (2024).
Molecules.
PubMed:
39203021

Black Mulberries (Morus nigra L.) Modulate Oxidative Stress and Beta-Amyloid-Induced Toxicity, Becoming a Potential Neuroprotective Functional Food.

The study shows that black mulberry extract is rich in antioxidants and has neuroprotective properties, potentially preventing neurodegenerative diseases. It also inhibits MAO-A enzyme and scavenges free radicals.

Cásedas G et al (2024).
Foods.
PubMed:
39200504

Innovative Postharvest Management for Hass Avocado at the Preclimacteric Stage: A Combined Technology with GABA and 1-MCP.

Researchers studied the use of GABA and 1-MCP to extend avocado shelf life by reducing chilling injury. The combined treatment improved fruit quality and delayed ripening and ethylene production, making it a recommended strategy for refrigerated storage.

Ruiz-Aracil MC et al (2024).
Foods.
PubMed:
39200412

Linalool and Geraniol Defend Neurons from Oxidative Stress, Inflammation, and Iron Accumulation in In Vitro Parkinson's Models.

Lavender and geranium essential oil compounds linalool and geraniol show potential in reducing oxidative stress, inflammation, and altering iron metabolism in in vitro Parkinson's models. Potential alternative therapy.

Pandur E et al (2024).
Antioxidants (Basel).
PubMed:
39199163

Schisandra chinensis (Turcz.) Baill neutral polysaccharides alleviate Parkinson's disease via effectively activating MCL-1 expression regulation of autophagy signaling.

SBP-1 polysaccharide from Schisandra chinensis may protect against Parkinson's disease by enhancing autophagy and targeting MCL-1 to improve neuronal survival. Potential treatment for PD.

Wang SY et al (2024).
Int J Biol Macromol.
PubMed:
39197630

Structural analysis, acetylcholinesterase inhibitory activity and immunoregulatory activity of two acidic polysaccharides from Chrysanthemum morifolium cv. Gongju.

Two polysaccharides from Chrysanthemum morifolium inhibit acetylcholinesterase and boost immune function. GJP-2 may enhance cognitive and immune function, paving the way for potential medical and food applications.

Wang Y et al (2024).
Int J Biol Macromol.
PubMed:
39197617