Neuroscience Studies

Rosemary extract activates oligodendrogenesis genes in mouse brain and improves learning and memory ability.

Study found that rosemary extract improved cognitive function in aging mice by reducing inflammation and increasing neurotransmitters. Potential therapy for cognitive dysfunction and aging.

GeneticsNeuroscience Rosmarinus officinalis
Sasaki K et al (2024).
Biomed Pharmacother.
DOI:
10.1016/j.biopha.2024.117350
PubMed:
39197189

Effects of Strawberry Tree Water Leaf Extract and Arbutin on Biochemical Markers and DNA Integrity in Brain Cells of Lewis Rats.

Study on the effects of strawberry tree extract and arbutin in rat brain tissue. Results show no harmful impact on antioxidant status or DNA integrity. Promising for potential nutraceutical development.

GeneticsNeuroscience Arbutus unedo
Benković V et al (2024).
Toxics.
DOI:
10.3390/toxics12080595
PubMed:
39195697

Effects of Mucuna pruriens (L.) DC. and Levodopa in Improving Parkinson's Disease in Rotenone Intoxicated Mice.

Preliminary study on Mucuna pruriens (MP) and Levodopa for Parkinson's disease showed both improved cognitive function and reduced neuroinflammation. MP may have similar effects as Levodopa, suggesting potential as a treatment.

Neuroscience Mucuna pruriens
Zaigham SB and Paeng DG (2024).
Curr Issues Mol Biol.
DOI:
10.3390/cimb46080545
PubMed:
39194762

Psidium exotic and native's species from Brazil abolish depression-like behavior and oxidative stress induced by corticosterone in mice.

Scientists studied the antidepressant and antioxidant effects of Psidium leaf extracts on mice. Results show potential in treating depression and diseases with high oxidative stress. Antioxidants could be beneficial.

ImmunologyNeuroscience Psidium guajavaPsidium guineense
Zeni ALB et al (2024).
Planta Med.
DOI:
10.1055/a-2404-3294
PubMed:
39191412

Long-Term Seizure Outcome With or Without Vagal Nerve Stimulation Therapy.

Researchers compared seizure control in patients with long-term VNS stimulation vs. those who stopped after >3 years. VNS-on had better long-term seizure control, important for treatment decisions.

Neuroscience Salvia
Gill S et al (2024).
Neurol Clin Pract.
DOI:
10.1212/CPJ.0000000000200358
PubMed:
39185099

Gastrodin against oxidative stress-inflammation crosstalk via inhibiting mtDNA/TLR9 and JAK2/STAT3 signaling to ameliorate ischemic stroke injury.

Gastrodin protects against stroke-induced inflammation and mitochondrial dysfunction by inhibiting JAK2/STAT3 signaling pathway, making it a potential therapy for cerebral ischemia.

CardiologyImmunologyNeuroscience Gastrodia elata
Zhang M et al (2024).
Int Immunopharmacol.
DOI:
10.1016/j.intimp.2024.113012
PubMed:
39182268

Exploring the therapeutic potential of Potentilla fragarioides var. major (Rosaceae) extract in Alzheimer's disease using in vitro and in vivo models: A multi-faceted approach.

EEPF from Potentilla fragarioides var. major inhibits Aβ aggregation, enhances free-radical scavenging, and alleviates memory impairment in AD models through multiple mechanisms. Promising potential for AD treatment.

Neuroscience Potentilla fragarioides
Sohn E et al (2024).
Neuroscience.
DOI:
10.1016/j.neuroscience.2024.08.029
PubMed:
39179018

Lingguizhugan decoction ameliorates cognitive impairment in AD-like mice by influencing the microbiome-gut-brain axis mediated by SCFAs.

Researchers studied Lingguizhugan decoction, a traditional Chinese herbal remedy, for its potential in treating Alzheimer's disease by influencing the gut-brain axis through gut microbiota modulation. This ancient remedy may offer novel therapeutic possibilities for AD.

GastroenterologyNeuroscience Atractylodes macrocephala
Du L et al (2024).
Phytomedicine.
DOI:
10.1016/j.phymed.2024.155942
PubMed:
39173279
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