Neuroscience Studies

Antidepressant-like and antioxidant effects of Morus nigra L. in rats subjected to the unpredictable chronic mild stress model.

Study shows Morus nigra leaf extract reduces depression-like behavior in stressed rats, possibly through antioxidant effects. Potential new treatment for depression.

Merida BF et al (2024).
Nat Prod Res.
PubMed:
39172975

The beneficial pharmacological effects of Uncaria rhynchophylla in neurodegenerative diseases: focus on alkaloids.

Summary: Traditional Chinese medicine Gouteng shows neuroprotective benefits in neurodegenerative diseases like Parkinson's and Alzheimer's. Compounds like corynoxine B offer potential for new drug development. Relevant for aging population health.

Chen L, Liu Y and Xie J (2024).
Front Pharmacol.
PubMed:
39170707

Extraction, Phytochemical profile, and neuroprotective activity of Phyllanthus emblica fruit extract against sodium valproate-induced postnatal autism in BALB/c mice.

Study evaluated EAFA extract's effect on VPA-induced autism in mice, showing improved behavior, antioxidant activity, reduced inflammation, and neuroprotection. EAFA extract may be a potential treatment for autism.

Gouda B et al (2024).
Heliyon.
PubMed:
39157403

Unlocking the possibilities of therapeutic potential of silymarin and silibinin against neurodegenerative Diseases-A mechanistic overview.

Silymarin from Silybum marianum plant is a potent antioxidant, liver protective, and potential neuroprotective agent with immunomodulatory properties. It shows promise for treating liver diseases, Alzheimer's, Parkinson's, and cerebral ischemia.

Ashique S et al (2024).
Eur J Pharmacol.
PubMed:
39154829

Olfactory sensory neuron population expansions influence projection neuron adaptation and enhance odour tracking.

Researchers studied how Drosophila sechellia evolved specialized olfactory pathways for detecting noni fruit. Increased sensory neuron populations lead to stronger tracking behavior, but not increased sensitivity. Understanding these mechanisms can help explain species-specific behavior in response to environmental cues.

Takagi S et al (2024).
Nat Commun.
PubMed:
39147786

Dose-Dependent Attenuation of the Efficacy of Clitoria ternatea by Cobalt Oxide Nanoparticles Against Diabetes-Induced Cognitive Impairment.

Clitoria ternatea extract shows potential for treating diabetes-induced cognitive impairment. Cobalt oxide nanoparticles may improve brain drug delivery, but high doses are neurotoxic. Low doses show neuroprotective effects, warranting further study.

Satpathy B et al (2024).
Mol Neurobiol.
PubMed:
39143449

Addressing GI Health Through the Bidirectional Modulation of the Gut-Brain Axis With Herbal Extracts: A Narrative Review.

Researchers studied the impact of functional constipation on quality of life and mental health. The gut-brain axis plays a role in functional gastrointestinal disorders. Traditional treatments have limitations, leading to interest in herbal supplements like ashwagandha and okra for symptom management.

Evans C and Kalman D (2024).
Cureus.
PubMed:
39139804