Neuroscience Studies

Sugarcane (Saccharum officinarum L.) induces psychostimulant, anxiolytic-like effects and improvement of motor performance in rats.

Sugarcane is traditionally used as a tonic and fatigue-fighting remedy. Preclinical studies in rats show that sugarcane leaf extract affects the central nervous and cardiovascular systems through dopaminergic pathways, potentially improving motor, emotional, and cognitive functions.

Ziroldo JC, Torres LMB and Gamberini MT (2024).
J Ethnopharmacol.
PubMed:
38908491

Scenting serenity: influence of essential-oil vaporization on dental anxiety - a cluster-randomized, controlled, single-blinded study (AROMA_dent).

Study shows essential-oil vaporization reduces dental anxiety, especially in females and those with high trait anxiety. Promising potential for alleviating dental fear and improving patient comfort. Further research needed.

Czakert J et al (2024).
Sci Rep.
PubMed:
38898054

Purpurin ameliorated neuropathic allodynia and hyperalgesia by modulating neuronal mitochondrial bioenergetics and redox status in type 1 diabetic mice.

Purpurin, a compound from Rubia tinctorum, relieves neuropathic pain in diabetic mice by enhancing bioenergetics and antioxidant effects. Could lead to improved therapy for diabetic patients with peripheral neuropathy.

Chen W et al (2024).
Eur J Pharmacol.
PubMed:
38897444

Identification of antidepressant constituents from Xiangfu-chuanxiong herbal medicine pair via spectrum-effect relationship analyses, molecular docking and corticosterone-induced PC12 cells.

Study evaluated XF-CX herbal medicine pair ratios for antidepressant effects. XF-CX (2:1) most effective. Identified potential antidepressant constituents. Beneficial for depression treatment mechanism and clinical application.

Li HJ et al (2024).
Fitoterapia.
PubMed:
38897250

New Value of Acorus tatarinowii/gramineus Leaves as a Dietary Source for Dementia Prevention.

Leaves of Schott and Solander show promise in treating dementia. Simple crush powder has strongest effect on tauopathy and other pathologies. Potential dietary source for dementia prevention.

Umeda T et al (2024).
Nutrients.
PubMed:
38892521

Investigating the Pharmacological Mechanisms of Total Flavonoids from Eucommia ulmoides Oliver Leaves for Ischemic Stroke Protection.

Study shows total flavonoids from EUL leaves can protect against nerve damage from ischemia by reducing oxidative stress, increasing cell survival rates, and modulating related pathways, suggesting potential therapeutic effects for ischemic stroke treatment.

Qin J et al (2024).
Int J Mol Sci.
PubMed:
38892459

Antidepressant-like Effects of Chinese Quince (Chaenomeles sinensis) Fruit Based on In Vivo and Molecular Docking Studies.

Chinese quince fruit extract (CSFE) contains compounds that improved depressive and anxiety-like behaviors in mice induced by corticosterone (CORT). CGA and neo-CGA from CSFE bind strongly to MAO-B, suggesting potential antidepressant effects.

Lim DW et al (2024).
Int J Mol Sci.
PubMed:
38892026

Effects of benzoic acid synthesized from Cinnamomum cassia by green chemistry on valproic acid-induced neurotoxicity in zebrafish embryos.

Researchers studied the effects of green-synthesized benzoic acid on autism-related gene expression in zebrafish embryos exposed to Valproic acid toxicity. Benzoic acid improved gene expression and antioxidant balance, showing potential for autism treatment.

Cansız D et al (2024).
Toxicol Mech Methods.
PubMed:
38888055