Neuroscience Studies

Sodium Houttuyfonate Prevents Seizures and Neuronal Cell Loss by Maintaining Glutamatergic System Stability in Male Rats with Kainic Acid-Induced Seizures.

SH (sodium houttuyfonate) showed antiseizure & neuroprotective effects in a rat model. It prevented glutamate level increase and altered glutamatergic system, similar to carbamazepine. Important potential alternative treatment for seizures.

Neuroscience Houttuynia cordata
Chang Y, Chen YJ and Wang SJ (2024).
Biomedicines.
DOI:
10.3390/biomedicines12061312
PubMed:
38927519

Neuroprotective Effect of Marrubium vulgare Extract in Scopolamine-Induced Cognitive Impairment in Rats: Behavioral and Biochemical Approaches.

The study found that the extract improved memory in rats by preserving cholinergic function, increasing NA levels, and restoring pCREB expression. It may have neuroprotective effects through modulation of cholinergic function and NA neurotransmission.

Neuroscience Marrubium vulgare
Lazarova M et al (2024).
Biology (Basel).
DOI:
10.3390/biology13060426
PubMed:
38927306

Two Olea europea extracts reduce deleterious effects in a model of neurotoxicity: involvement of the endoplasmic reticulum.

Scientists tested two olive extract variations on lead-induced neurotoxicity in human neurons, finding sonicated extract s-OE more effective in reducing damage due to its antioxidant properties and greater efficiency, offering potential for neuroprotection.

Neuroscience Olea europaea
Maiuolo J et al (2024).
Planta Med.
DOI:
10.1055/a-2353-1469
PubMed:
38925154

Gomisin N rescues cognitive impairment of Alzheimer's disease by targeting GSK3β and activating Nrf2 signaling pathway.

Gomisin N from Schisandra chinensis has neuroprotective effects in Alzheimer's disease by upregulating antioxidant proteins and improving cognitive function in AD models through the GSK3β/Nrf2 signaling pathway. Potentially promising therapeutic agent.

Neuroscience Schisandra chinensis
Song M et al (2024).
Phytomedicine.
DOI:
10.1016/j.phymed.2024.155811
PubMed:
38924927

Neuroinflammation and acetylcholinesterase inhibition potentials of acyclic monoterpenoids isolated from Cymbopogon distans (Nees ex Steud.) Will. Watson.

Aromatic plant Nees ex Steud. inhibits neuroinflammation in BV2 microglial cells. Compound RS4 from plant's oil shows potential to treat neurodegenerative disorders by inhibiting AChE.

Neuroscience Cymbopogon distans
Singh S et al (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2369918
PubMed:
38919044

Relationship of Curcumin with Aging and Alzheimer and Parkinson Disease, the Most Prevalent Age-Related Neurodegenerative Diseases: A Narrative Review.

Curcumin, a bioactive phytochemical found in turmeric, shows promise in combating age-related neurological diseases due to its antioxidant and anti-inflammatory properties. Consuming curcumin may help prevent cognitive decline and memory disorders in the elderly.

Neuroscience Curcuma longa
Turer BY and Sanlier N (2024).
Nutr Rev.
DOI:
10.1093/nutrit/nuae079
PubMed:
38916925

Effect of Saffron Versus Selective Serotonin Reuptake Inhibitors (SSRIs) in Treatment of Depression and Anxiety: A Meta-analysis of Randomized Controlled Trials.

Researchers have found that saffron may have benefits for depression and anxiety. This could lead to new natural treatments for mental health issues.

Neuroscience Crocus sativus
Shafiee A et al (2024).
Nutr Rev.
DOI:
10.1093/nutrit/nuae076
PubMed:
38913392

Neuroprotective effects of Gypenosides: A review on preclinical studies in neuropsychiatric disorders.

Gynostemma pentaphyllum gypenosides show promise in treating neuropsychiatric disorders. More research needed for clinical applications. Important for potential neuroprotective properties and improving human health.

Neuroscience Gynostemma pentaphyllum
Liang G et al (2024).
Eur J Pharmacol.
DOI:
10.1016/j.ejphar.2024.176766
PubMed:
38908668
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