All Studies

Intestinal Microbiome Metabolism of Cranberry (Vaccinium macrocarpon) Proanthocyanidin Dimers, but Not Trimers, Is Altered by Dysbiosis in Ulcerative Colitis Ex Vivo.

Cranberries have chemical variations that affect how they are metabolized by gut bacteria. Healthy microbiomes produce more beneficial compounds from cranberries than ulcerative colitis microbiomes. The metabolism of a specific cranberry compound called procyanidin B2 is key for this difference.

Gastroenterology Vaccinium macrocarpon
Diaz MS, Mertens-Talcott SU and Talcott ST (2024).
J Agric Food Chem.
DOI:
10.1021/acs.jafc.4c00042
PubMed:
38350030

n-Butanol fraction of moringa seed attenuates arsenic intoxication by regulating the uterine inflammatory and apoptotic pathways.

Researchers found that the n-butanol fraction of Moringa oleifera seed (NB) effectively repaired uterine damage caused by arsenic poisoning. NB reduced lipid peroxidation, increased antioxidant enzyme activity, restored uterine histomorphology, and normalized mRNA and protein expression of inflammatory and apoptotic indicators. The interaction between glucomoringin and methyl glucosinolate may limit caspase-3 activity, making NB a potential therapy for arsenic-induced uterine damage.

Immunology Moringa oleifera
Jana S et al (2024).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-024-32213-4
PubMed:
38349492

Differential amplification of the subtelomeric satellite DNA JcSAT1 in the genus Jatropha L. (Euphorbiaceae).

Researchers investigated the repetitive DNA sequence JcSAT1 in various Jatropha species and found variations in abundance and distribution. This suggests the evolution of JcSAT1 through ectopic recombination near telomeres, with a potential amplification event in Jatropha curcas.

Genetics Jatropha curcas
Ribeiro T et al (2024).
Genetica.
DOI:
10.1007/s10709-024-00204-5
PubMed:
38349466

Effects of the protective and therapeutic effect of yogurt enriched with Citrus sinensis essential oil against ibuprofen-induced gastric ulcer in elderly rats.

This study found that adding Citrus sinensis essential oil to yogurt increased acidity, total solids, and ash values. Rats fed with this functional yogurt had fewer gastric ulcer lesions compared to the control group. This suggests that yogurt with C. sinensis EO may help reduce the severity of ulcers and improve health.

GastroenterologyPhytochemistry Citrus sinensis
Polat Z et al (2024).
J Food Sci.
DOI:
10.1111/1750-3841.16937
PubMed:
38349052

Complex insoluble dietary fiber alleviates obesity and liver steatosis, and modulates the gut microbiota in C57BL/6J mice fed a high-fat diet.

Researchers studied the effects of insoluble dietary fiber (IDF) on obesity, inflammation, and diabetes. IDF has positive effects on these conditions, making it important for overall health.

GastroenterologyObesity Daucus carota
Liu Z et al (2024).
J Sci Food Agric.
DOI:
10.1002/jsfa.13380
PubMed:
38348948

Programmable Biosynthesis of Plant-Derived 4'-Deoxyflavone Glycosides by an Unconventional Yeast Consortium.

Scientists developed a yeast-based platform to produce pharmaceutical components found in rare plants. This method reduces environmental impact and allows for the synthesis of multiple compounds. The study provides insight into biosynthesizing plant-derived components for therapeutic use.

Phytochemistry Scutellaria baicalensis
Kang Y et al (2024).
Small Methods.
DOI:
10.1002/smtd.202301371
PubMed:
38348919

Antifungal activity and potential mechanism of action of Huangqin decoction against Trichophyton rubrum.

Huangqin decoction inhibits growth of dermatophyte, and damages its cell membrane and enzyme activities, revealing significant anti-dermatophyte potential.

Antimicrobial Scutellaria baicalensis
Shen C et al (2024).
J Med Microbiol.
DOI:
10.1099/jmm.0.001805
PubMed:
38348868

Genome assembly and transcriptomic analysis to elucidate the ability of Nasonovia ribisnigri to break host plant resistance.

Scientists studied the aphid Nasonovia ribisnigri, a pest of lettuce, that developed resistance to a resistant cultivar. They identified a single gene in the aphid that allows it to overcome the resistance mechanism in lettuce. This finding helps understand the mechanisms of resistance and inform future pest management strategies.

Genetics Lactuca sativa
Garrett D et al (2024).
Insect Mol Biol.
DOI:
10.1111/imb.12894
PubMed:
38348538
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