Structural feature-based strategy for the identification of diterpene alkaloids in Aconitum carmichaeli Debeaux.

Researchers used LC-MS to identify 230 diterpene alkaloids in raw Aconitum carmichaelii and 466 in fermented Aconitum carmichaelii, improving identification accuracy and discovering potential new compounds.

Liu Z et al (2023).

Fitoterapia.

DOI:

10.1016/j.fitote.2023.105761

PubMed:

38036079

Genome-wide identification of microsatellites for mapping, genetic diversity and cross-transferability in wheat (Triticum spp).

Fandade V et al (2024).

Gene.

DOI:

10.1016/j.gene.2023.148039

PubMed:

38036075

Uncovering Mechanism and Efficacy of Salvia Miltiorrhiza-Safflower in Cerebral Ischemia-Reperfusion Injury.

This study investigates the molecular regulation and therapeutic effectiveness of the Danshen-Honghua herb pair for cerebral ischemia (CI). By identifying common targets and pathways, it suggests that DH may activate the TNF-α/JNK signaling pathway for CI treatment.

Zhang Y et al (2024).

Neuroscience.

DOI:

10.1016/j.neuroscience.2023.11.021

PubMed:

38036060

Six new coumarins from the roots of Toddalia asiatica and their anti-inflammatory activities.

Scientists discovered six new compounds, toddasirins A-F, from Toddalia asiatica roots. The compounds were structurally elucidated and assessed for anti-inflammatory activity. Compounds 1-3 and 6 exhibited significant inhibition of nitric oxide (NO) production in RAW 264.7 cells induced by lipopolysaccharide.

He H et al (2023).

Chin J Nat Med.

DOI:

10.1016/S1875-5364(23)60480-7

PubMed:

38035940

Reversal of mitochondrial permeability transition pore and pancreas degeneration by chloroform fraction of Ocimum gratissimum (L.) leaf extract in type 2 diabetic rat model.

This study investigated the effects of the chloroform fraction of (L.) leaf (CFOG) in reversing tissue wastage in diabetes. CFOG reduced insulin resistance, improved pancreatic cell regeneration, and inhibited mitochondrial dysfunction. The main active compound in CFOG was lupanol. This suggests the potential use of CFOG as an alternative therapy for diabetes.

Salemcity AJ et al (2023).

Front Pharmacol.

DOI:

10.3389/fphar.2023.1231826

PubMed:

38035005

The extract from Portulaca oleracea L. rehabilitates skin photoaging via adjusting miR-138-5p/Sirt1-mediated inflammation and oxidative stress.

Purslane extract protects against skin aging caused by UV radiation by reducing oxidative damage and inflammation. It regulates miR-138-5p/Sirt1 signaling, making it a potential natural product for skin care.

Qu L, Wang F and Ma X (2023).

Heliyon.

DOI:

10.1016/j.heliyon.2023.e21955

PubMed:

38034793

The effects of titanium dioxide (TiO(2)) nanoparticles on physiological, biochemical, and antioxidant properties of Vitex plant (Vitex agnus - Castus L).

Spraying titanium dioxide nanoparticles on plants improved root and shoot growth but reduced leaf weight. It also increased chlorophyll levels and antioxidant enzyme activity without affecting proline and soluble protein content, suggesting potential benefits for plant growth and biochemical properties.

Moshirian Farahi SM et al (2023).

Heliyon.

DOI:

10.1016/j.heliyon.2023.e22144

PubMed:

38034643

Pulsatillae radix extract alleviates DSS-induced colitis via modulating gut microbiota and inflammatory signaling pathway in mice.

Researchers studied the effectiveness and mechanisms of Baitouweng decoction (BD), a Traditional Chinese Medicine, in treating ulcerative colitis (UC). Understanding this could help improve UC treatment, reducing its global impact on public health.

Li X et al (2023).

Heliyon.

DOI:

10.1016/j.heliyon.2023.e21869

PubMed:

38034600