GeoBotanical: All Studies

5689.

Exploring the mechanism of resistance to vincristine in breast cancer cells using transcriptome sequencing technology.

Scientists investigated the development of resistance to vincristine (VCR), a chemotherapy drug used for breast cancer treatment. By analyzing gene expression and splicing events, they identified changes in the VCR-resistant breast cancer cell line. This study lays the foundation for understanding VCR resistance and developing potential treatments.

Cancer Genetics Catharanthus roseus

Chen Y et al (2023).; Oncol Lett.
DOI:: 10.3892/ol.2023.14089
PubMed:: 37920438

5690.

Astragalin: a food-origin flavonoid with therapeutic effect for multiple diseases.

This article reviews the natural source, pharmacokinetics, and pharmacological activities of astragalin (AG), a natural flavonoid found in various edible plants. AG has therapeutic effects against several diseases, making it a potential functional food for disease therapy.

Phytochemistry Cuscuta chinensis Morus alba

Chen J et al (2023).; Front Pharmacol.
DOI:: 10.3389/fphar.2023.1265960
PubMed:: 37920216

5691.

Repeated loss of the ability of a wild pepper disease resistance gene to function at high temperatures suggests that thermoresistance is a costly trait.

Study examines resistance genes in domesticated pepper relative and finds lower resistance in cultivated populations. Genes show different recognition and expression at various temperatures. Domestication leads to loss of resistance, with broad-spectrum resistance at higher temperatures having fitness costs.

Genetics Capsicum annuum

Poulicard N et al (2023).; New Phytol.
DOI:: 10.1111/nph.19371
PubMed:: 37920100

5692.

Identifying cis-Acting Elements Associated with the High Activity and Endosperm Specificity of the Promoters of Genes Encoding Low-Molecular-Weight Glutenin Subunits in Common Wheat (Triticum aestivum).

Scientists identified two genes involved in the expression regulation of low-molecular-weight glutenin subunits (LMW-GSs) in wheat. Understanding this could lead to the development of wheat as a bioreactor for producing beneficial substances.

Genetics Triticum aestivum

Qu G et al (2023).; J Agric Food Chem.
DOI:: 10.1021/acs.jafc.3c04209
PubMed:: 37919930

5693.

Comparative transcriptome analysis of dioecious floral development in Trachycarpus fortunei using Illumina and PacBio SMRT sequencing.

Trachycarpus fortunei is an economically and aesthetically valuable plant. This study used sequencing to understand how the plant determines its male or female flowers, which could have implications for better cultivation and hybridization practices.

Genetics Trachycarpus fortunei

Xiao F et al (2023).; BMC Plant Biol.
DOI:: 10.1186/s12870-023-04551-x
PubMed:: 37919651

5694.

Phytohormones and candidate genes synergistically regulate fruitlet abscission in Areca catechu L.

Researchers studied the process of fruitlet abortion in Areca catechu, a plant with low yield due to frequent abscission. They analyzed hormone levels in abscised and non-abscised fruitlets to understand the physiological and molecular variations.

Genetics Areca catechu

Li J et al (2023).; BMC Plant Biol.
DOI:: 10.1186/s12870-023-04562-8
PubMed:: 37919647

5695.

The variations in gene expression of GAPDH in Ocimum basilicum cultivars under drought-induced stress conditions.

Researchers investigate the role of a protein in basil plants under drought stress. They study the gene encoding this protein, predict its role in oxidative stress, and examine its expression patterns under water scarcity. Findings may aid crop improvement strategies.

Genetics Ocimum basilicum

Ranjbar M et al (2023).; Environ Sci Pollut Res Int.
DOI:: 10.1007/s11356-023-30549-x
PubMed:: 37919503

5696.

The effect of Ganoderma lucidum polysaccharide extract on sensitizing prostate cancer cells to flutamide and docetaxel: an in vitro study.

The study found that Ganoderma lucidum polysaccharide, when used in combination with Docetaxel and Flutamide, significantly enhanced apoptosis, reduced cell migration and colonization, and decreased the expression of prostate cancer biomarkers. This suggests that Ganoderma lucidum polysaccharide could be a new potential therapy for prostate cancer.

Cancer Ganoderma lucidum

Rahimnia R et al (2023).; Sci Rep.
DOI:: 10.1038/s41598-023-46118-8
PubMed:: 37919464