All Studies

An optimized machine learning method for predicting wogonin therapy for the treatment of pulmonary hypertension.

Wogonin, derived from Scutellaria baicalensis Georgi, can mitigate the progression of pulmonary hypertension (PH) in mice. A noninvasive prediction method using feature selection (BSCDWOA-KELM) can accurately screen key indicators in PH datasets. This method can be used to predict wogonin therapy for PH.

Li Y et al (2023).
Comput Biol Med.
PubMed:
37591162

Transcription factors MdMYC2 and MdMYB85 interact with ester aroma synthesis gene MdAAT1 in apple.

Jasmonic acid (JA) stimulates ester aroma production in apples. Methyl jasmonate (MeJA) increases ester synthesis by upregulating genes MdMYC2, MdMYB85, and MdAAT1. Their interaction promotes aroma synthesis.

Li LX et al (2023).
Plant Physiol.
PubMed:
37590971

Thymoquinone Effect on Leishmania tropica/infantum and Leishmania-Infected Macrophages.

This study examines the effects of Thymoquinone, a compound found in Nigella Sativa, on Leishmania parasites and infected macrophages. It explores potential therapeutic benefits for Leishmania infection.

KarimiPourSaryazdi A et al (2023).
Acta Parasitol.
PubMed:
37589882

Limonoids from neem (Azadirachta Indica A. Juss.) are potential anticancer drug candidates.

Neem tree extracts contain limonoids with potent medicinal properties. These compounds have been found to display anticancer effects by preventing cancer cell growth, inflammation, invasion, and drug resistance. Neem limonoids offer potential as natural compounds for cancer prevention and therapy.

Nagini S, Palrasu M and Bishayee A (2023).
Med Res Rev.
PubMed:
37589457

EVALUATION OF THE COMPLEX USE OF PLANT TEST-SYSTEMS TO DETERMINE THE NATURE AND INTENSITY OF THE MUTAGENIC BACKGROUND OF THE ENVIRONMENT.

Study evaluated the use of plant test-systems to identify the specific effects of mutagens on hereditary apparatus. Important for making informed decisions in the lab.

Shvets LS et al (2023).
Pol Merkur Lekarski.
PubMed:
37589106

Network pharmacology based anti-diabetic attributes of bioactive compounds from Ocimum gratissimum L. through computational approach.

This study identified key compounds in L. plant that target protein molecules of Diabetes Mellitus. These compounds have potential therapeutic effects in managing DM through multiple mechanisms.

Halayal RY et al (2023).
Saudi J Biol Sci.
PubMed:
37588570