Ling-Gui-Qi-Hua formula alleviates left ventricular myocardial fibrosis in rats with heart failure with preserved ejection fraction by blocking the transforming growth factor-β1 /Smads signaling pathway.
The researchers studied the LGQH decoction, a traditional Chinese medicine formula, and found it has cardioprotective effects on heart failure. The active ingredients and anti-fibrotic mechanism are still unknown.
- Shi Y et al (2023).
- J Ethnopharmacol.
- PubMed:
- 37385575