Cancer Studies

Exploring the Anti-Cancer Potential of Hispidin: A Comprehensive In Silico and In Vitro Study on Human Osteosarcoma Saos2 Cells.

Hispidin, extracted from the wild mushroom, shows anti-neoplastic properties, non-toxicity, and potential as a bone cancer inhibitor. Identified and characterized using spectroscopic and computational techniques. Good inhibitor for bone cancer targets.

Benarous K et al (2024).
Chem Biodivers.
PubMed:
38456582

Cytotoxic activity of ethyl acetate extract of Chromolaena odorata on MCF7 and T47D breast cancer cells.

Researchers tested ethyl acetate extract of a plant against breast cancer cells, showing selective and promising anticancer activity. This natural compound may be developed as an effective treatment for breast cancer.

Yusuf H, Novia H and Fahriani M (2023).
Narra J.
PubMed:
38455634

Limonin inhibits the stemness of cancer stem-like cells derived from colorectal carcinoma cells potentially via blocking STAT3 signaling.

Limonin, a common ingredient in citrus fruits, shows potential for antitumor effects on colorectal cancer cells and cancer stem-like cells, which could improve outcomes for patients with CRC.

Zhang WF et al (2024).
World J Clin Oncol.
PubMed:
38455137

The Efficacy of Ganoderma lucidum Extracts on Treating Endometrial Cancer: A Network Pharmacology Approach.

Study demonstrates Ganoderma lucidum extracts inhibit endometrial cancer by activating Rap1 signaling pathway, inhibiting proliferation, promoting apoptosis, and blocking cell cycle. Important for potential cancer treatment research.

Shi M et al (2024).
Reprod Sci.
PubMed:
38448739

Therapeutic potential of traditional Chinese medicine in the prevention and treatment of digestive inflammatory cancer transformation: Portulaca oleracea L. as a promising drug.

POL in TCM treats inflammation and tumors in the digestive system. Its diverse compounds have strong anti-inflammatory and anti-cancer effects. Important for potential medical advancements.

Shao G et al (2024).
J Ethnopharmacol.
PubMed:
38447616

Network pharmacology and experimental verification study on the mechanism of Hedyotis diffusa Willd in treating colorectal cancer.

Study assessed Hedyotis diffusa Willd effects on CRC using network pharmacology & experimental validation. Identified potential targets, key genes, pathways, & validated anti-CRC effects in vitro. Important for developing new CRC treatments.

Yuan X et al (2024).
Naunyn Schmiedebergs Arch Pharmacol.
PubMed:
38446216

Artemisia argyi extracts overcome lapatinib resistance via enhancing TMPRSS2 activation in HER2-positive breast cancer.

Artemisia argyi can help overcome lapatinib resistance in HER2-positive breast cancer by activating TMPRSS2, leading to cell death and potentially improving therapy outcomes.

Ho CY et al (2024).
Environ Toxicol.
PubMed:
38445457

RN0D, a galactoglucan from Panax notoginseng flower induces cancer cell death via PINK1/Parkin mitophagy.

RN0D from Panax notoginseng induces mitochondrial dysfunction in cancer cells, leading to cell death through ATP deprivation and mitophagy. Targets Galectin-3 and activates PINK1/Parkin pathway, showing promise as an anticancer therapeutic.

Ji M et al (2024).
Carbohydr Polym.
PubMed:
38431406