Cancer Studies

Preliminary Study on Total Component Analysis and In Vitro Antitumor Activity of Eucalyptus Leaf Residues.

This study analyzed eucalyptus residue and found 55 compounds, including triterpenoids with antitumor activity. Triterpenoids could be enhanced to 82% and showed inhibitory effects on breast, gastric, and cervical cancer cells. Potential for development as antitumor drugs.

Wu J et al (2024).
Molecules.
PubMed:
38257193

Exploring the Anticancer Potential of Traditional Thai Medicinal Plants: A Focus on Dracaena loureiri and Its Effects on Non-Small-Cell Lung Cancer.

Traditional medicinal plants in Thailand, (DLEE), (FREE), and (HPEE), were evaluated for their anti-cancer properties against A549 lung adenocarcinoma cells. Only DLEE showed cytotoxic effects, inhibiting cell proliferation and inducing apoptosis. This suggests that DLEE may have potential as a treatment for NSCLC.

Huang X et al (2024).
Plants (Basel).
PubMed:
38256842

Investigation of Epilobium hirsutum L. Optimized Extract's Anti-Inflammatory and Antitumor Potential.

An optimized extract of L demonstrated comparable anti-inflammatory properties to a control group and reduced tumor-associated inflammation and oxidative stress, suggesting its potential as a natural therapeutic agent.

Vlase AM et al (2024).
Plants (Basel).
PubMed:
38256751

Enhanced Chemoprevention of Prostate Cancer by Combining Arctigenin with Green Tea and Quercetin in Prostate-Specific Phosphatase and Tensin Homolog Knockout Mice.

Researchers tested the combination of arctigenin, green tea, and quercetin to enhance the anticancer effects on prostate cancer. They found a strong synergistic effect in vitro and significant inhibition of tumorigenesis in vivo. Clinical trials are needed to confirm efficacy in humans.

Hao Q et al (2024).
Biomolecules.
PubMed:
38254705

Antimicrobial and Antiproliferative Effects of Zingiberaceae Oils: A Natural Solution for Oral Health.

This study evaluated the antibacterial and antiproliferative activity of essential oils from four Zingiberaceae species for oral care. Curcuma xanthorrhiza and Curcuma mangga oils showed strong antibacterial properties, suggesting they could be used as natural alternatives in oral care products. Further research is needed to explore their therapeutic potential.

Amil MA et al (2024).
Chem Biodivers.
PubMed:
38253795

Essential oil from Citrus depressa peel exhibits antimicrobial, antioxidant and cancer chemopreventive effects.

Researchers investigated the potential benefits of essential oils extracted from discarded citrus peels in preventing diseases caused by pathogens and oxidative stress. This utilization of agricultural waste promotes a sustainable agricultural economy and environmental protection.

Weng YX et al (2024).
J Sci Food Agric.
PubMed:
38252712

Detection of Sialic Acid to Differentiate Cervical Cancer Cell Lines Using a Sambucus nigra Lectin Biosensor.

Scientists developed a biosensor using gold nanoparticles and a lectin to detect abnormal sialic acid in cervical cancer cells. This method can differentiate between cancerous and non-cancerous cells, aiding in the early detection of cervical cancer.

Zamudio Cañas R et al (2024).
Biosensors (Basel).
PubMed:
38248411

Triptolide induces apoptosis and cytoprotective autophagy by ROS accumulation via directly targeting peroxiredoxin 2 in gastric cancer cells.

Triptolide, an active compound from Tripterygium wilfordii, kills gastric cancer cells by increasing reactive oxygen species (ROS) levels. It targets peroxiredoxins-2 (PRDX2) to inhibit its antioxidant activity, leading to apoptosis. PRDX2 could be a potential therapeutic target for anti-gastric cancer agents.

Chen P et al (2024).
Cancer Lett.
PubMed:
38246224