Kaempferol-3-O-(2″-O-galloyl-β-D-glucopyranoside): a novel neuroprotective agent from Diospryros kaki against cerebral ischemia-induced brain injury.

Diospyros kaki L.f. leaf extract contains a potent flavonoid compound (9) that reduces brain injury, improves impairments, preserves blood-brain barrier, and suppresses oxidative stress, suggesting its potential for treating ischemic-induced brain damage.

Nguyen LTT et al (2023).

J Nat Med.

DOI:

10.1007/s11418-023-01765-z

PubMed:

38143256

Regulatory effects of curcumin on nitric oxide signaling in the cardiovascular system.

Curcumin, a component of Curcuma longa, shows promise in treating cardiovascular diseases (CVDs) due to its ability to increase nitric oxide (NO) synthesis and impact NO signaling pathways, improving endothelial function and offering anti-inflammatory and antioxidant benefits.

Abolfazli S et al (2024).

Nitric Oxide.

DOI:

10.1016/j.niox.2023.12.003

PubMed:

38141926

Corrigendum to "Study on the anti-mitochondrial apoptosis mechanism of Erigeron breviscapus injection based on UPLC-Q-TOF-MS metabolomics and molecular docking in rats with cerebral ischemia-reperfusion injury" [J. Ethnopharmacol. 319 (Part 2) (2024) 117310].

Zhang J et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117596

PubMed:

38141517

Songorine ameliorates LPS-induced sepsis cardiomyopathy by Wnt/β-catenin signaling pathway-mediated mitochondrial biosynthesis.

Songorine (SGR), a natural product derived from Aconitum carmichaeli, improves cardiac function and reduces inflammation in septic cardiomyopathy (SCM) by activating the Wnt/β-catenin signaling pathway and promoting mitochondrial biosynthesis. SGR could be a potential treatment for SCM.

Chen M et al (2023).

Naunyn Schmiedebergs Arch Pharmacol.

DOI:

10.1007/s00210-023-02897-5

PubMed:

38133657

Effects of Acute Beetroot Juice and Sodium Nitrate on Selected Blood Metabolites and Response to Transient Ischemia: A Crossover Randomized Clinical Trial.

Consumption of nitrate-rich products like beetroot juice can alter the nitrate-nitrite-nitric oxide pathway, which has implications for cardiovascular health and exercise performance in humans.

Jurga J et al (2024).

J Nutr.

DOI:

10.1016/j.tjnut.2023.12.018

PubMed:

38110180

Metagenomic sequencing revealed the regulative effect of Danshen and Honghua herb pair on the gut microbiota in rats with myocardial ischemia injury.

DHHP, a Chinese herb pair, relieves myocardial ischemia in rats by regulating gut microbiota. It improves diversity and increases beneficial bacteria while reducing harmful bacteria, offering potential for MI treatment.

Du SB et al (2024).

FEMS Microbiol Lett.

DOI:

10.1093/femsle/fnad133

PubMed:

38100390

Acute and short-term beetroot juice nitrate-rich ingestion enhances cardiovascular responses following aerobic exercise in postmenopausal women with arterial hypertension: A triple-blinded randomized controlled trial.

Postmenopausal women experience elevated blood pressure due to reduced levels of nitric oxide synthases (NOS). Understanding this helps manage hypertension and develop targeted treatments.

Benjamim CJR et al (2024).

Free Radic Biol Med.

DOI:

10.1016/j.freeradbiomed.2023.11.039

PubMed:

38092272

Effect of Lavandula angustifolia and Cananga odorata on decrease of blood pressure in high blood pressure volunteers: A randomized controlled trial.

Researchers evaluated the effectiveness and safety of sticker pads infused with lavender and ylang ylang oil in reducing blood pressure as an alternative treatment for hypertension.

Napavichayanun S et al (2023).

Explore (NY).

DOI:

10.1016/j.explore.2023.11.013

PubMed:

38087747