Diabetes Studies

Diabetic wound healing potential of silk sericin protein based hydrogels enriched with plant extracts.

Silk sericin-based hydrogels with plant extracts help heal diabetic wounds faster by reducing inflammation and promoting tissue regeneration. Use 4% sericin+4% banyan+4% onion hydrogel for best results.

Zahoor S et al (2023).
Int J Biol Macromol.
PubMed:
37276909

Low glycemic index potato biscuits alleviate physio-histological damage and gut dysbiosis in rats with type-2 diabetes mellitus induced by high-sugar and high-fat diet and streptozotocin.

This study found that low-glycemic index (GI) potato biscuits with oat bran and inulin improved type 2 diabetes in rats by reducing blood glucose levels and reversing metabolic disorders. These biscuits also positively affected the gut microbiota.

Zhao R et al (2023).
J Nutr Biochem.
PubMed:
37276891

Proteomics and transcriptomics explore the effect of mixture of herbal extract on diabetic wound healing process.

This study explores the potential use of a mixture of five herbal extracts in treating diabetic foot ulcers. Current methods are expensive and have limitations.

Liu Y et al (2023).
Phytomedicine.
PubMed:
37267693

HR-LCMS and evaluation of anti-diabetic activity of Hemidesmus indicus (anantmool): Kinetic study, and molecular modelling approach.

This study identified Hemidesmus indicus as a potential source for antidiabetic medications. The herb showed high extractive yield and inhibited carbohydrate hydrolytic enzymes. Molecular modeling techniques confirmed its potential as an inhibitor of alpha-amylase and alpha-glucosidase, suggesting it could be developed as a lead for type-2 diabetes medications.

Kumari S et al (2023).
Comput Biol Chem.
PubMed:
37263051

Cinnamomum cassia on Arterial Stiffness and Endothelial Dysfunction in Type 2 Diabetes Mellitus: Outcomes of a Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

This study examined the effects of for patients with type 2 diabetes. It found that administration reduced body weight, BMI, and HbAc, but had no significant impact on arterial stiffness, endothelial dysfunction, blood pressure, glucose, and lipids.

Delgadillo-Centeno JS et al (2023).
J Med Food.
PubMed:
37262194

Sanguisorba officinalis L. promotes diabetic wound healing in rats through inflammation response mediated by macrophage.

Chinese medicine Sanguisorba officinalis L. extract (ESO) accelerates diabetic wound healing by reducing inflammation through blocking NF-κB/NLRP3 signaling pathway. Promising treatment option.

Song J et al (2023).
Phytother Res.
PubMed:
37260161