Immunology Studies

Effects of Harvest Time and Hydrodistillation Time on Yield, Composition, and Antioxidant Activity of Mint Essential Oil.

This study found that harvesting spearmint at 9 a.m. and distilling it for 60 minutes resulted in the highest menthol content and antioxidant activity. It suggests that sun exposure and longer distillation times decrease menthol content and alter the chemical composition.

Marques SPPM et al (2023).
Molecules.
PubMed:
38005307

The Protective Effect of Marsdenia tenacissima against Cisplatin-Induced Nephrotoxicity Mediated by Inhibiting Oxidative Stress, Inflammation, and Apoptosis.

This study shows that the traditional Chinese medicine (TCM) MT can enhance the anti-tumor effect of cisplatin (Cis) while reducing its toxic side effects, specifically nephrotoxicity. MT improves renal function, decreases inflammation, and regulates apoptosis through the Nrf2 and NF-κB pathways. Use MT as an adjuvant to mitigate Cis-induced nephrotoxicity.

Zhang Z et al (2023).
Molecules.
PubMed:
38005304

Ultrasonic-Assisted Extraction of Antioxidants from Perilla frutescens Leaves Based on Tailor-Made Deep Eutectic Solvents: Optimization and Antioxidant Activity.

Researchers found that extracting antioxidants from Perilla leaves using choline chloride-based deep eutectic solvents (DESs) had high antioxidant activity. This eco-friendly method could have various applications, but its cytotoxicity and biodegradability need further investigation.

Jiao P et al (2023).
Molecules.
PubMed:
38005276

Zaluzanin C Alleviates Inflammation and Lipid Accumulation in Kupffer Cells and Hepatocytes by Regulating Mitochondrial ROS.

Zaluzanin C (ZC), a compound found in plants, has anti-inflammatory and antioxidant effects. It protects liver cells by reducing inflammation, improving mitochondrial function, and enhancing lipid metabolism. ZC could be an effective treatment for liver protection.

Jung JW et al (2023).
Molecules.
PubMed:
38005205

Effect of E. cava and C. indicum Complex Extract on Phorbol 12-Myristate 13-Acetate (PMA)-Stimulated Inflammatory Response in Human Pulmonary Epithelial Cells and Particulate Matter (PM)(2.5)-Induced Pulmonary Inflammation in Mice.

The study found that the natural composite ED could reduce lung inflammation caused by fine particulate matter. It inhibited gene expression and reduced cellular accumulation and mucus secretion, indicating its potential as a therapeutic agent for respiratory diseases.

Lee SG, Park CH and Kang H (2023).
Pharmaceutics.
PubMed:
38004599

Rubia cordifolia L. Attenuates Diabetic Neuropathy by Inhibiting Apoptosis and Oxidative Stress in Rats.

The study investigated the impact of L. (L.) roots in diabetic neuropathy using a rat model. It examined potential neuroprotective, antidiabetic, and analgesic mechanisms. This research is relevant for understanding diabetic neuropathy treatment options.

Bana S et al (2023).
Pharmaceuticals (Basel).
PubMed:
38004451

Protective Effect of Urtica dioica Extract against Oxidative Stress in Human Skin Fibroblasts.

This study examined the impact of nettle extract on human skin fibroblasts under oxidative stress. The extract showed high antioxidant potential, protecting cells from damage and reducing ROS levels. This suggests that nettle extract could be a beneficial and safe ingredient in skincare products.

Skalska-Kamińska A et al (2023).
Life (Basel).
PubMed:
38004322

The Synergistic Effect of Quince Fruit and Probiotics (Lactobacillus and Bifidobacterium) on Reducing Oxidative Stress and Inflammation at the Intestinal Level and Improving Athletic Performance during Endurance Exercise.

Endurance exercise can harm the intestines, but a study showed that consuming a combination of quince and probiotics protected the intestines and improved exercise performance by increasing antioxidant and anti-inflammatory activities. This could be beneficial for athletes.

Herrera-Rocha KM et al (2023).
Nutrients.
PubMed:
38004161