Immunology Studies

A glucuronogalactomannan isolated from Tetrastigma hemsleyanum Diels et Gilg: Structure and immunomodulatory activity.

TL;DR: STHP-5, a polysaccharide from Tetrastigma hemsleyanum, stimulates macrophages and activates TLR4, potentially serving as a novel immunomodulator.

Mao Z et al (2024).
Carbohydr Polym.
PubMed:
38494202

Cytisine-N-methylene-(5,7,4(')-trihydroxy)- isoflavone ameliorates ischemic stroke-induced brain injury in mouse by regulating the oxidative stress and BDNF-Trkb/Akt pathway.

LY01, from Sophora alopecuroides L, shows neuroprotection and potential for ischemic stroke treatment. Further research needed for mechanism and efficacy.

Li Y, Fan F and Liu Q (2024).
Eur J Pharmacol.
PubMed:
38493912

Phytochemical composition and in vitro antioxidant and antimicrobial activities of Bersama abyssinica F. seed extracts.

Study on Ethiopian medicinal plant, Bersama abyssinica, showed antioxidant & antimicrobial benefits. Rich in phytochemicals, GC-MS analysis revealed 30 volatile compounds. Seeds possess high antioxidant, antibacterial, and antifungal activities, suggesting potential for drug discovery.

Alemu B et al (2024).
Sci Rep.
PubMed:
38491116

Marrubium vulgare Extract Improves Spatial Working Memory and Oxidative Stress Damage in Scopolamine-Treated Rats.

Researchers studied the potential benefits of Marrubium vulgare, or 'white horehound,' on Alzheimer's disease. Results suggest it may protect against neuronal loss, oxidative stress, and improve short-term memory. Promising for future treatments.

Lazarova MI et al (2024).
J Alzheimers Dis.
PubMed:
38489175

Kaempferitrin attenuates unilateral ureteral obstruction-induced renal inflammation and fibrosis in mice by inhibiting NOX4-mediated tubular ferroptosis.

Kaempferitrin from Bauhinia forficata leaves inhibits tubular ferroptosis, reducing renal inflammation and fibrosis in CKD. It protects renal function, decreases iron levels, and inhibits NOX4-mediated ferroptosis, offering potential therapeutic value for CKD.

Li J et al (2024).
Phytother Res.
PubMed:
38487990

Antiobesity and antidiabetes effects of Cyperus rotundus rhizomes presenting protein tyrosine phosphatase, dipeptidyl peptidase 4, metabolic enzymes, stress oxidant and inflammation inhibitory potential.

"Tubers extract inhibits key enzymes, reduces inflammation in diabetic rats, protects pancreatic beta-cells, and modulates hepatic enzymes. Promising potential for preventing and treating obesity and diabetes."

Abdella FIA et al (2024).
Heliyon.
PubMed:
38486768

Phytoconstituent analysis, anti-inflammatory, antimicrobial and anticancer effects of nano encapsulated Convolvulus arvensis L. extracts.

Convolvulus arvensis L. extracts show potential as anti-bacterial, anti-inflammatory, and anti-cancer agents due to their chemical composition. Useful for nanotechnology applications in drug delivery and biomedicine.

Osman EEA et al (2024).
BMC Complement Med Ther.
PubMed:
38486187