Capparis spinosa Promoted BDNF and Antioxidant Enzyme Levels to Protect Against Learning and Memory Deficits Induced by Scopolamine.

Scientists studied the effects of C. spinosa extract on memory problems in rats treated with Scop. The extract showed potential in improving memory and reducing oxidative stress, suggesting it could be beneficial for Alzheimer's disease.

Hosseini M et al (2023).

Cent Nerv Syst Agents Med Chem.

DOI:

10.2174/1871524923666230719121439

PubMed:

37563815

Nardostachys jatamansi and levodopa combination alleviates Parkinson's disease symptoms in rats through activation of Nrf2 and inhibition of NLRP3 signaling pathways.

Combining levodopa with traditional Chinese medicine (NJ) can effectively alleviate Parkinson's disease (PD) symptoms, offering a potential holistic treatment option.

Li J et al (2023).

Pharm Biol.

DOI:

10.1080/13880209.2023.2244176

PubMed:

37559448

Four Pairs of Neuroprotective Aryldihydronapthalene-type Lignanamide Enantiomers from the Herbs of Solanum lyratum.

Researchers isolated and identified several new compounds from a plant, and studied their effects on neuroprotection and inhibition of AchE. Compound 4a showed significant neuroprotective effects, and compound 1a exhibited strong inhibition of AchE.

Mi SH et al (2023).

Chem Biodivers.

DOI:

10.1002/cbdv.202300941

PubMed:

37548481

Ginkgo biloba extract (EGb-761) confers neuroprotection against ischemic stroke by augmenting autophagic/lysosomal signaling pathway.

Ginkgo biloba extract (EGb-761) promotes autophagic/lysosomal signaling in neurons and reduces infarction size, neurological deficits, and neuron death in ischemic stroke. It could be a potential new treatment target.

Zang R et al (2023).

J Neuroimmunol.

DOI:

10.1016/j.jneuroim.2023.578101

PubMed:

37536050

Hyperoside Prevents Aβ42-Induced Neurotoxicity in PC12 Cells and Caenorhabditis elegans.

Wang K et al (2023).

Mol Neurobiol.

DOI:

10.1007/s12035-023-03521-6

PubMed:

37535309

Comparative Chemical Composition and Acetylcholinesterase (AChE) Inhibitory Potential of Cinnamomum camphora and Cinnamomum tamala.

The study analyzed the chemical composition of essential oils from Cinnamomum species, finding high levels of certain compounds. The oils showed potential as acetylcholinesterase inhibitors, useful for pharmaceutical and fragrance industries.

Rawat A et al (2023).

Chem Biodivers.

DOI:

10.1002/cbdv.202300666

PubMed:

37533252

Huannao Yicong decoction ameliorates cognitive deficits in APP/PS1/tau triple transgenic mice by interfering with neurotoxic interaction of Aβ-tau.

Zhang H et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.116985

PubMed:

37532075

Tenuigenin promotes non-rapid eye movement sleep via the GABA(A) receptor and exerts somnogenic effect in a MPTP mouse model of Parkinson's disease.

Zhang D et al (2023).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2023.115259

PubMed:

37531785