Herb pair of Polygala tenuifolia Willd and Acorus tatarinowii Schott decoction attenuates seizures and alleviates anxiety in mice: Evidence for modulating inflammation, alleviating oxidative stress and mediating GABA pathway.

PTAT decoction, a traditional medicine, showed significant antiepileptic and anxiolytic effects in mice through modulation of GABA neurotransmission and reduction of inflammation, suggesting potential as a natural treatment for epilepsy.

Xie Y et al (2023).

Pak J Pharm Sci.

PubMed:

37530166

Hirami lemon (Citrus reticulata var. depressa) modulates the gut-brain axis in a chronic mild stress-induced depression mouse model.

Researchers investigated the antidepressant effects of Hirami lemon on mice. The fruit extract and essential oil reversed depression and anxiety-like behaviors by restoring gut microbiota dysbiosis. This study suggests that Hirami lemon could be a natural antidepressant treatment.

Tsai PH et al (2023).

Food Funct.

DOI:

10.1039/d3fo01301d

PubMed:

37526032

Aucubin improves chronic unpredictable mild stress-induced depressive behavior in mice via the GR/NF-κB/NLRP3 axis.

The study examined the therapeutic effect of aucubin (AU), the main component of Eucommia ulmoides Oliv (EUO), on depression in mice. AU improved depression-like behavior by promoting intranuclear expression of glucocorticoid receptor (GR) and inhibiting inflammation-driven cell pyroptosis.

Liu P et al (2023).

Int Immunopharmacol.

DOI:

10.1016/j.intimp.2023.110677

PubMed:

37523973

Efficacy and Anti-Inflammatory Activity of Ashwagandha Sustained-Release Formulation on Depression and Anxiety Induced by Chronic Unpredictable Stress: in vivo and in vitro Studies.

Ashwagandha is a natural herb known as an adaptogen that aids in managing stress. It is safe and effective, making it beneficial for stress relief.

KrishnaRaju AV et al (2023).

J Exp Pharmacol.

DOI:

10.2147/JEP.S407906

PubMed:

37521489

Neuroprotective potency of mangiferin against 3-nitropropionic acid induced Huntington's disease-like symptoms in rats: possible antioxidant and anti-inflammatory mechanisms.

Mangiferin, a compound in plants, has protective effects against Huntington's disease by reducing symptoms, improving cognitive and motor function, and decreasing oxidative damage and inflammation in the brain. It may be a potential treatment for HD.

Lum PT et al (2023).

Front Pharmacol.

DOI:

10.3389/fphar.2023.1189957

PubMed:

37521470

Therapeutic effect of Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. leaves on ischemic stroke via the microbiota-gut-brain axis.

Wang R et al (2023).

Phytother Res.

DOI:

10.1002/ptr.7947

PubMed:

37518502

Association of medicinal plant consumption with all-cause mortality and cognitive impairment in older adult: A large prospective cohort study.

This study examines the impact of consuming medicinal plants like Panax ginseng on overall mortality and cognitive impairment but lacks evidence from large-scale studies.

Tao L et al (2023).

Phytomedicine.

DOI:

10.1016/j.phymed.2023.154995

PubMed:

37516089

The Role of Gut Microbiota in Anxiety, Depression, and Other Mental Disorders as Well as the Protective Effects of Dietary Components.

Imbalance of gut bacteria affects mental health; dietary components like probiotics and spices can help prevent mental disorders.

Xiong RG et al (2023).

Nutrients.

DOI:

10.3390/nu15143258

PubMed:

37513676