Neuroscience Studies

Antioxidative and neuroprotective potential of Acorus calamus linn. and Cordia dichotoma G. Forst. In Alzheimer's type dementia in rodent.

The researchers tested plant extracts of Acorus calamus and Cordia dichotoma on mice with Alzheimer's-like symptoms caused by scopolamine. The extracts improved behavioral and biochemical parameters, indicating potential for treating cognitive disorders and neurodegenerative diseases.

Malik R et al (2023).
Brain Res.
PubMed:
37793605

Neuroprotective potential of Marsilea quadrifolia Linn against monosodium glutamate-induced excitotoxicity in rats.

Scientists investigated the neuroprotective potential of against monosodium glutamate (MSG)-induced excitotoxicity in rats. The study found that improved locomotor activity, memory, and learning, and reduced neuronal damage. The findings suggest that could be used as a therapeutic treatment for neurological disorders.

Subramanian A et al (2023).
Front Pharmacol.
PubMed:
37781695

Cactus flour (Opuntia ficus-indica) reduces brain lipid peroxidation and anxious-like behavior in old Wistar rats.

This study found that elderly rats fed with cactus flour showed reduced anxiety-like behavior and decreased brain lipid peroxidation. Cactus pear could potentially prevent or treat anxiety in aging individuals due to its nutritional contents.

Moura RL et al (2023).
Physiol Behav.
PubMed:
37778453

Ilexchinene, a new seco-ursane triterpenoid from the leaves of Ilex chinensis with therapeutic effect on neuroinflammation by attenuating the MAPK/NF-κB signaling pathway.

Scientists discovered that the leaves of Ilex chinensis contain triterpenoids with anti-neuroinflammatory properties. These novel compounds have the potential to combat neurodegenerative disorders.

Shao S et al (2023).
Phytomedicine.
PubMed:
37776618

Matrine mediated neuroprotective potential in experimental multiple sclerosis: Evidence from CSF, blood markers, brain samples and in-silico investigations.

Researchers investigated the role of JAK/STAT and PPAR-gamma signaling pathways in multiple sclerosis (MS). They found that matrine, a compound derived from a plant, showed potential neuroprotective effects by inhibiting STAT-3 and mTOR and promoting PPAR-gamma expression. Matrine treatment improved MS symptoms by modulating these pathways.

Chhabra S et al (2023).
J Neuroimmunol.
PubMed:
37774554

Neuroprotective potential of Cordia dichotoma in Parkinson's syndrome induced by haloperidol: An animal study.

This study investigated the potential neuroprotective role of [plant name] in a model of haloperidol-induced Parkinson's disease. It aims to find a safe and effective therapeutic regimen to manage this neurodegenerative disorder.

Bhavani K et al (2023).
Saudi Pharm J.
PubMed:
37771955

Neuroprotective α-pyrones from Nigrospora oryzae, an endophytic fungus residing in Taxus chinensis var. mairei.

Scientists discovered eight previously unknown pyrones and six known pyrones from an endophytic fungus. Some of these pyrones show potential as neuroprotective agents, making this research important for understanding natural chemical diversity and expanding biofunction possibilities.

Fan ZY et al (2023).
Phytochemistry.
PubMed:
37769958