Neuroscience Studies

Role of Acorus calamus in preventing depression, anxiety, and oxidative stress in long-term socially isolated rats.

Study found that social isolation stress and individual housing cause cognitive issues and psychiatric diseases. Acorus calamus (AC) has potential therapeutic value for neurological disorders. This study examined AC's antidepressant and antioxidative effects on rats subjected to long-term social isolation stress.

Rai AR et al (2023).
Vet World.
PubMed:
37766700

Investigating the Therapeutic Potential of Plants and Plant-Based Medicines: Relevance to Antioxidant and Neuroprotective Effects.

Various plant extracts were examined for their ability to reduce oxidative stress in brain cells. Elderberry, Queen Garnet plum, and clove showed neuroprotective effects, while elderberry also demonstrated treatment effects. Further research is needed to explore their potential as therapies for oxidative stress-related disorders.

May N et al (2023).
Nutrients.
PubMed:
37764696

Effects of Aphrodite (an Herbal Compound) on SSRI-Induced Sexual Dysfunctions and Depression in Females with Major Depressive Disorder: Findings from a Randomized Clinical Trial.

Aphrodite, an herbal blend, was found to improve symptoms of sexual dysfunction, depression, and anxiety in females with major depression disorder and SSRI-induced sexual dysfunction. Additional research is needed to understand how Aphrodite achieves these effects.

Shahmoradi N et al (2023).
Medicina (Kaunas).
PubMed:
37763782

In Silico Neuroprotective Effects of Specific Rheum palmatum Metabolites on Parkinson's Disease Targets.

Study finds metabolites in plant roots may have neuroprotective effects and potential as Parkinson's disease drugs. Emodin shows strong binding activity and stability, while other compounds inhibit specific targets. Study suggests link between redox-mediating activities and PD-related protein targets.

Garcia PJB et al (2023).
Int J Mol Sci.
PubMed:
37762232

Assessment of Bio-Compounds Content, Antioxidant Activity, and Neuroprotective Effect of Red Cabbage (Brassica oleracea var. Capitata rubra) Processed by Convective Drying at Different Temperatures.

Dehydrated red cabbage, with higher temperatures resulting in increased bio-compound concentrations, demonstrated neuroprotective effects lasting up to 48 hours, making it a potential functional food ingredient for Parkinson's disease treatment.

Vega-Galvez A et al (2023).
Antioxidants (Basel).
PubMed:
37760092

Molecular and Pharmacokinetic Aspects of the Acetylcholinesterase-Inhibitory Potential of the Oleanane-Type Triterpenes and Their Glycosides.

This study explores the acetylcholinesterase-inhibitory potential of various compounds found in the bark of (Combreatceae). Arjunetin and arjunglucoside I can cross the blood-brain barrier. These compounds show potential as cognition-enhancing agents and have a high binding energy. The kinetics of AChE inhibition were also tested.

Stępnik K, Kukula-Koch W and Płaziński W (2023).
Biomolecules.
PubMed:
37759757

Study on network pharmacology of Ginkgo biloba extract against ischaemic stroke mechanism and establishment of UPLC-MS/MS methods for simultaneous determination of 19 main active components.

Ginkgo biloba extract (GBE) is effective for treating stroke, but we don't know the active ingredients or how it works. You should care because understanding its mechanism can help us develop better treatments.

Yin CY et al (2023).
Phytochem Anal.
PubMed:
37758241

Neuroprotective neolignan glycosides from the pseudobulbs of Bletilla striata.

Researchers discovered four new neolignan glycosides in Bletilla striata, which showed promising neuroprotective effects against glutamate-induced PC12 cell injury. These compounds are the first of their kind found in the genus Bletilla, indicating the potential of Bletilla striata as a source of anti-neurodegenerative agents.

Zhou M et al (2023).
Fitoterapia.
PubMed:
37757922