Neuroscience Studies

Neutral polysaccharide from Gastrodia elata alleviates cerebral ischemia-reperfusion injury by inhibiting ferroptosis-mediated neuroinflammation via the NRF2/HO-1 signaling pathway.

This study looked at how a polysaccharide from Gastrodia elata called NPGE affects the interaction between ferroptosis and neuroinflammation during cerebral ischemia-reperfusion injury. It found that NPGE has potential effects against oxidative stress and inflammation in CIRI neuropathology.

CardiologyNeuroscience Gastrodia elata
Zhang Y et al (2023).
CNS Neurosci Ther.
DOI:
10.1111/cns.14456
PubMed:
37752806

Sensory neuron population expansion enhances odour tracking through relaxed projection neuron adaptation.

Researchers compared the olfactory sensory neuron (OSN) populations of two species and found that the one with larger expansions performed better in odor plume-tracking assays, highlighting the significance of sensory neuron expansions in species-specific behavior.

Neuroscience Morinda citrifolia
Takagi S et al (2023).
bioRxiv.
DOI:
10.1101/2023.09.15.556782
PubMed:
37745467

Rubus fruticosus leaf extract inhibits vascular dementia-induced memory impairment and neuronal loss by attenuating neuroinflammation.

Researchers found that a leaf extract alleviated memory impairment and reduced inflammation in the brain, potentially offering a solution for vascular dementia.

Neuroscience Rubus fruticosus
Sung NS et al (2023).
Anat Cell Biol.
DOI:
10.5115/acb.23.195
PubMed:
37743615

Attention-deficit/hyperactivity disorder and inflammation: natural product-derived treatments-a review of the last ten years.

This review explores herbal treatments for ADHD, examining their effects on humans and animals and their potential to modify inflammation. It may offer non-pharmacological options with fewer side effects for ADHD treatment.

ImmunologyNeuroscience Crocus sativusGinkgo biloba
Martins A et al (2023).
Inflammopharmacology.
DOI:
10.1007/s10787-023-01339-1
PubMed:
37740887

Chemical characterization, anti-struvite crystal, anti-inflammatory, analgesic, and antidepressant activities of Papaver rhoeas L. root and leaf extracts.

Scientists investigated the effects of root and leaf extracts from Papaver rhoeas on struvite crystals, inflammation, pain, and depression. No previous data available. Useful for potential treatment applications.

ImmunologyNeurosciencePain Papaver rhoeas
Hmamou A et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117208
PubMed:
37739099

The efferent connections of the orbitofrontal, posterior parietal, and insular cortex of the rat brain.

This study provides a digital resource of microscopic images from rat brain experiments, showing the structural connectivity of the orbitofrontal, posterior parietal, and insular cortices.

Neuroscience Phaseolus vulgaris
Reiten I et al (2023).
Sci Data.
DOI:
10.1038/s41597-023-02527-y
PubMed:
37735463

Graph Attention Network based mapping of knowledge relations between chemical spaces of Nuclear factor kappa B and Centella asiatica.

Researchers used deep learning and a graph-based system to study the immune system target NF-κB. They found nine molecules from Centella asiatica that could regulate NF-κB and need further investigation.

Neuroscience Centella asiatica
P V et al (2023).
Comput Biol Chem.
DOI:
10.1016/j.compbiolchem.2023.107955
PubMed:
37734134

Design and development of donepezil hydrochloride loaded nanostructured lipid carriers for efficient management of Alzheimer's disease.

Scientists developed tiny lipid carriers for a drug called donepezil hydrochloride, which could help treat Alzheimer's disease effectively. You should care because it could potentially improve the treatment of Alzheimer's disease.

Neuroscience Nigella sativa
Tekade AR et al (2023).
Drug Dev Ind Pharm.
DOI:
10.1080/03639045.2023.2262035
PubMed:
37733474
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